- 1. Fluoride exposure disrupts the synthesis
of collagen and leads to the breakdown of collagen in bone, tendon, muscle,
skin, cartilage, lungs, kidney and trachea.
- A.K. Susheela and Mohan Jha, "Effects
of Fluoride on Cortical and Cancellous Bone Composition," IRCS Medical
Sciences: Library Compendium, Vol. 9, No.11, pp. 1021-1022 (1981); Y. D.
Sharma, "Effect of Sodium Fluoride on Collagen Cross-Link Precursors,"
Toxicological Letters, Vol. 10, pp. 97-100 (1982); A. K. Susheela and D.
Mukerjee, "Fluoride poisoning and the Effect of Collagen Biosynthesis
of Osseous and Nonosseous Tissue," Toxicological European Research,
Vol. 3, No.2, pp. 99-104 (1981); Y.D. Sharma, "Variations in the Metabolism
and Maturation of Collagen after Fluoride Ingestion," Biochemica et
Biophysica Acta, Vol. 715, pp. 137-141 (1982); Marian Drozdz et al., "Studies
on the Influence of Fluoride Compounds upon Connective Tissue Metabolism
in Growing Rats" and "Effect of Sodium Fluoride With and Without
Simultaneous Exposure to Hydrogen Fluoride on Collagen Metabolism,"
Journal of Toxicological Medicine, Vol. 4, pp. 151-157 (1984).
- 2. Fluoride stimulates granule formation
and oxygen consumption in white blood cells, but inhibits these processes
when the white blood cell is challenged by a foreign agent in the blood.
- Robert A. Clark, "Neutrophil Iodintion
Reaction Induced by Fluoride: Implications for Degranulation and Metabolic
Activation," Blood, Vol. 57, pp. 913-921 (1981).
- 3. Fluoride depletes the energy reserves
and the ability of white blood cells to properly destroy foreign agents
by the process of phagocytosis. As little as 0.2 ppm fluoride stimulates
superoxide production in resting white blood cells, virtually abolishing
phagocytosis. Even micro-molar amounts of fluoride, below 1 ppm, may seriously
depress the ability of white blood cells to destroy pathogenic agents.
- John Curnette, et al, "Fluoride-mediated
Activation of the Respiratory Burst in Human Neutrophils," Journal
of Clinical Investigation, Vol. 63, pp. 637-647 (1979); W. L. Gabler and
P. A. Leong, ., "Fluoride Inhibition of Polymorphonumclear Leukocytes,"
Journal of Dental Research, Vol. 48, No. 9, pp. 1933-1939 (1979); W. L.
Gabler, et al., "Effect of Fluoride on the Kinetics of Superoxide
Generation by Fluoride," Journal of Dental Research, Vol. 64, p. 281
(1985); A. S. Kozlyuk, et al., "Immune Status of Children in Chemically
Contaminated Environments," Zdravookhranenie, Issue 3, pp. 6-9 (1987)
- 4. Fluoride confuses the immune system
and causes it to attack the body's own tissues, and increases the tumor
growth rate in cancer prone individuals.
- Alfred Taylor and Nell C. Taylor, "Effect
of Sodium Fluoride on Tumor Growth," Proceedings of the Society for
Experimental Biology and Medicine, Vol. 119, p. 252 (1965); Shiela Gibson,
"Effects of Fluoride on Immune System Function," Complementary
Medical Research, Vol. 6, pp. 111-113 (1992); Peter Wilkinson, "Inhibition
of the Immune System With Low Levels of Fluorides," Testimony before
the Scottish High Court in Edinburgh in the Case of McColl vs. Strathclyde
Regional Council, pp. 17723-18150, 19328-19492, and Exhibit 636, (1982);
D. W. Allman and M. Benac, "Effect of Inorganic Fluoride Salts on
Urine and Cyclic AMP Concentration in Vivo," Journal of Dental Research,
Vol. 55 (Supplement B), p. 523 (1976); S. Jaouni and D. W. Allman, "Effect
of Sodium Fluoride and Aluminum on Adenylate Cyclase and Phosphodiesterase
Activity," Journal of Dental Research, Vol. 64, p. 201 (1985)
- 5. Fluoride inhibits antibody formation
in the blood.
- S. K. Jain and A. K. Susheela, "Effect
of Sodium Fluoride on Antibody Formation in Rabbits," Environmental
Research, Vol. 44, pp. 117-125 (1987)
- 6. Fluoride depresses thyroid activity.
- Viktor Gorlitzer Von Mundy, "Influence
of Fluorine and Iodine on the Metabolism, Particularly on the Thyroid Gland,"
Muenchener Medicische Wochenschrift, Vol. 105, pp. 182-186 (1963); A. Benagiano,
"The Effect of Sodium Fluoride on Thyroid Enzymes and Basal Metabolism
in the Rat," Annali Di Stomatologia, Vol. 14, pp. 601-619 (1965);
Donald Hillman, et al., "Hypothyroidism and Anemia Related to Fluoride
in Dairy Cattle," Journal of Dairy Science, Vol. 62, No.3, pp. .416-423
(1979); V. Stole and J. Podoba, "Effect of Fluoride on the Biogenesis
of Thyroid Hormones," Nature, Vol. 188, No. 4753, pp. 855-856 (1960);
Pierre Galleti and Gustave Joyet, "Effect of Fluorine on Thyroid Iodine
Metabolism and Hyperthyroidism," Journal of Clinical Endocrinology
and Metabolism, Vol. 18, pp. 1102-1110 (1958)
- 7. Fluorides have a disruptive effect
on various tissues in the body.
- T. Takamorim "The Heart Changes
in Growing Albino Rats Fed on Varied Contents of Fluorine," The Toxicology
of Fluorine Symposium, Bern, Switzerland, Oct 1962, pp. 125-129; Vilber
A. O. Bello and Hillel J. Gitelman, "High Fluoride Exposure in Hemodialysis
Patients," American Journal of Kidney Diseases, Vol. 15, pp. 320-324
(1990); Y. Yoshisa, "Experimental Studies on Chronic Fluorine Poisoning,"
Japanese Journal of Industrial Health, Vol. 1, pp. 683-690 (1959)
- 8. Fluoride promotes development of bone
- J.K. Mauer, et al., "Two-Year Cacinogenicity
Study Of Sodium Fluoride In Rats," Journal of the National Cancer
Institute, Vol. 82, pp. 1118-1126 (1990); Proctor and Gamble "Carcinogenicity
Studies with Sodium Fluoride in Rats" National Institute of Environmenrtal
Health Sciences Presentation, July 27, 1985; S. E. Hrudley et al., "Drinking
Water Fluoridation and Osteosarcoma," Canadian Journal of Public Health,
Vol. 81, pp. 415-416 (1990); P. D. Cohn, "A Brief Report on the Association
of Drinking Water Fluoridation and Incidence of Osteosarcoma in Young Males,"
New Jersey Department of Health, Trenton, New Jersey, Nov. 1992; M. C.
Mahoney et al., "Bone Cancer Incidence Rates in New York," American
Journal of Public Health, Vol. 81, pp. 81, 475 (1991); Irwin Herskowitz
and Isabel Norton, "Increased Incidence of Melanotic Tumors Following
Treatment with Sodium Fluoride," Genetics Vol. 48, pp. 307-310 (1963);
J. A. Disney, et al., " A Case Study in Testing the Conventional Wisdom:
School Based Fluoride Mouth Rinse Programs in the USA," Community
Dentistry and Oral Epidemiology, Vol. 18, pp. 46-56 (1990); D. J. Newell,
"Fluoridation of Water Supplies and Cancer - An Association?,"
Applied Statistics, Vol. 26, No. 2, pp. 125-135 (1977)
- 9. Fluorides cause premature aging of
the human body.
- Nicholas Leone, et al., "Medical
Aspects of Excessive Fluoride in a Water Supply," Public Health Reports,
Vol. 69, pp. 925-936 (1954); J. David Erikson, "Mortality of Selected
Cities with Fluoridated and Non-Fluoridated Water Supplies," New England
Journal of Medicine, Vol. 298, pp. 1112-1116 (1978); "The Village
Where People Are Old Before Their Time," Stern Magazine, Vol. 30,
pp. 107-108, 111-112 (1978)
- 10. Fluoride ingestion from mouth rinses
and dentifrices in children is extremely hazardous to biological development,
life span and general health.
- Yngve Ericsson and Britta Forsman, "Fluoride
Retained From Mouth Rinses and Dentifrices In Preschool Children,"
Caries Research, Vol. 3, pp. 290-299 (1969); W. L. Augenstein, et al.,
"Fluoride Ingestion In Children: A Review Of 87 Cases," Pediatrics,
Vol. 88, pp. 907-912, (1991); Charles Wax, "Field Investigation Report,"
State of Maryland Department of Health and Mental Hygiene, March 19, 1980,
67 pages; George Waldbott, "Mass Intoxication from Over-Fluoridation
in Drinking Water," Clinical Toxicology, Vol. 18, No.5, pp. 531-541
- Other Facts
- The contents of a family size tube of
fluoridated toothpaste is enough to kill a 25 pound child.
- In 1991, the Akron (Ohio) Regional Poison
Center reported that "death has been reported following ingestion
of 16mg/kg of fluoride. Only 1/10 of an ounce of fluoride could kill a
100 pound adult. According to the Center, "fluoride toothpaste contains
up to 1mg/gram of fluoride." Even Proctor and Gamble, the makers of
Crest, acknowledge that a family-sized tube "theoretically contains
enough fluoride to kill a small child."
- Fluorides have been used to modify behavior
and mood of human beings.
- It is a little known fact that fluoride
compounds were added to the drinking water of prisoners to keep them docile
and inhibit questioning of authority, both in Nazi prison camps in World
War II and in the Soviet gulags in Siberia.
- Fluorides are medically categorized as
protoplasmic poisons, which is why they are used to kill rodents.
- The September 18, 1943 issue of the Journal
of the American Medical Association, states, "fluorides are general
protoplasmic poisons, changing the permeability of the cell membrane by
inhibiting certain enzymes. The exact mechanisms of such actions are obscure."
- Fluoride consumption by human beings
increases the general cancer death rate.
- In 1975 Dr. John Yiamouyiannis published
a preliminary survey which showed that people in fluoridated areas have
a higher cancer death rate than those in non-fluoridated areas. The National
Cancer Institute attempted to refute the studies. Later in 1975 Yiamouyiannis
joined with Dr. Dean Burk, chief chemist of the National Cancer Institute
(1939-1974) in performing other studies which were then included in the
Congressional Record by Congressman Delaney, who was the original author
of the Delaney Amendment, which prohibited the addition of cancer-causing
substances to food used for human consumption. Both reports confirmed the
existence of a link between fluoridation and cancer. (Note: Obviously Dr.
Burk felt free to agree with scientific truth only after his tenure at
National Cancer Institute ended, since his job depended on towing the party
- Fluorides have little or no effect on
decay prevention in humans.
- In 1990 Dr. John Colquhoun was forced
into early requirement in New Zealand after he conducted a study on 60,000
school children and found no difference in tooth decay between fluoridated
and unfluoridated areas. He additionally found that a substantial number
of children in fluoridated areas suffered from dental fluorosis. He made
the study public.
- There is no scientific data that shows
that fluoride mouth rinses and tablets are safe for human use.
- In 1989 a study by Hildebolt, et al.
on 6,000 school children contradicted any alleged benefit from the use
of sodium fluorides. A 1990 study by Dr. John Yiamouyiannis on 39,000 school
children contradicted any alleged benefits from the use of sodium fluorides.
In 1992 Michael Perrone, a legislative assistant in New Jersey, contacted
the FDA requesting all information regarding the safety and effectiveness
of fluoride tablets and drops. After 6 months of stalling, the FDA admitted
they had no data to show that fluoride tablets or drops were either safe
or effective. They informed Perrone that they will "probably have
to pull the tablets and drops off the market."
- The fact that fluoride toothpastes and
school based mouth rinses are packaged in aluminum accentuates the effect
on the body.
- In 1976, Dr. D. Allman and coworkers
from Indiana University School of Medicine fed animals 1 part-per-million
(ppm) fluoride and found that in the presence of aluminum, in a concentration
as small as 20 parts per billion, fluoride is able to cause an even larger
increase in cyclic AMP levels. Cyclic AMP inhibits the migration rate of
white blood cells, as well as the ability of the white blood cell to destroy
pathogenic (disease-causing) organisms. Reference: Journal of Dental Research,
Vol. 55, Sup B, p. 523, 1976, "Effect of Inorganic Fluoride Salts
on Urine and Tissue Cyclic AMP Concentration in Vivo". (Note: It is
no small accident that toothpaste tubes containing fluoride are often made
- "Fluoridation is the greatest case
of scientific fraud of this century"
- Robert Carlton, Ph. D., former U. S.
EPA scientist on "Marketplace" Canadian Broadcast Company, Nov.
- "Regarding fluoridation, the EPA
should act immediately to protect the public, not just on the cancer data,
but on the evidence of bone fractures, arthritis, mutagenicity and other
- William Marcus, Ph. D., senior EPA toxicologist,
Covert Action, Fall 1992, p. 66
- The above information has been posted
at the Leading Edge Research Group Internet Web Site.
- Leading Edge Research Group P.O. Box
7530 Yelm, WA 98597 <email@example.com