SIGHTINGS


 
Ethnically Targeted Bio-Weapons Getting Closer To Reality
1-21-99
 
LONDON (Reuters) - Biological and genetic weapons designed to kill specific ethnic or racial groups are no longer the stuff of science fiction, British researchers warned on Thursday.
 
A designer plague that would only kill Serbs or a toxin engineered to affect Israelis or Kurds does not exist yet but advances in biotechnology and the mapping of all human genes could be misused to develop lethal weapons within five to 10 years.
 
Dr Vivienne Nathanson, the head of health policy research at the British Medical Association (BMA), said genetic information is already being used to enhance biological weapons.
 
``It would be a tragedy if in 10 years time the world faces the reality of genetically engineered and possibly genetically targeted weapons,'' she told a news conference to launch a new book entitled ``Biotechnology Weapons and Humanity.''
 
``It is not technology and information that is available today, but it is becoming increasingly available. We do have a window of opportunity before weapons of that type are manufactured to make sure we have effective measures of prevention.''
 
The book by Professor Malcolm Dando, of the Department of Peace Studies at the University of Bradford in northern England, paints a terrifying picture of the power of biological weapons.
 
The release of 100 kg (220 pounds) of anthrax spores from canisters planted in a major city could wipe out up to three million people.
 
The book traces the history of the development and use of biological weapons and warns that scientific knowledge has been exploited in the past and is likely to be misused in the future unless international action is taken.
 
``We believe biological weapons will become an increasing weapon in terrorist activity,'' said Nathanson. ``An ethnically targeted weapon becomes more of a reality.''
 
The designer weapon works on a similar principle to gene therapy but instead of replacing faulty genes that don't work it exploits genetic variations to target its victims.
 
For example, micro-organisms could be genetically engineered to attack known receptor sites on the cell membrane or viruses could be targeted at specific DNA sequences inside cells.
 
William Assche, the chairman of the BMA's board of science and education, said the report is designed to raise public, medical and political awareness about the dangers of biological weapons.
 
It urges the international community to strengthen the 1972 Biological and Toxin Weapons Convention to improve verification procedures. It also calls on doctors and scientists to protect the integrity of their work and to monitor the potential use of genome mapping.
 
``Getting rid of weapons once they are produced is very difficult. Governments may be reluctant to give up weapons that the rest of the world find unacceptable. Terrorists certainly will be,'' said Nathanson.
 
``We still have the chance to strengthen the ban on these weapons. We must do so now and we must make sure the ban is policed effectively.''
 
 
 
Ethno-Specific Genetic Weapons Termed Serious Threat
 
BBC Online Health 1-21-99
 
Advances in genetic knowledge could be misused to develop powerful biological weapons that could be tailored to strike at specific ethnic groups, the British Medical Association has warned.
 
A BMA report Biotechnology, Weapons and Humanity says that concerted international action is necessary to block the development of new, biological weapons.
 
It warns the window of opportunity to do so is very narrow as technology is developing rapidly and becoming ever more accessible.
 
"Recipes" for developing biological agents are freely available on the Internet, the report warns.
 
As genetic manipulation becomes a standard laboratory technique, there is a risk that this new information will also become widely available.
 
Procedures to monitor against the misuse of this new knowledge are urgently needed, the BMA says.
 
Abuse of knowledge
 
The report identifies two principal ways in which advancing genetic knowledge could be misused for weapons development: * Genetic information is already being used to "improve" elements of biological weapons, for example by increasing their antibiotic resistance. These developments raise the spectre of highly targeted biological weapons being used on the battlefield. * Weapons could theoretically be developed which affect particular versions of genes clustered in specific ethnic or family groups. Although genetic weapons which target a particular ethnic group are not currently a practical possibility, the report concludes it would be complacent to assume that they could never be developed in the future.
 
Humans from apparently widely divergent social groups actually have more similarities than differences in their genetic make up. But differences do exist and as the Human Genome Project advances, these differences can increasingly be identified.
 
The BMA report warns that legitimate research into microbiological agents and genetically targeted therapeutic agents could be difficult to distinguish from research geared towards developing more effective weapons.
 
The BMA says that urgent action is needed to strengthen the Biological and Toxin Weapons Convention.
 
This has not been effective in prohibiting the development of biological weapons, the BMA says, because it does not have adequate verification provisions.
 
The BMA has called on doctors and medical organisations to campaign against the development of biological weapons.
 
Serious threat
 
Dr Vivienne Nathanson, BMA Head of Health Policy Research said: "The history of humanity is a history of war.
 
"Scientific advances quickly lead to developments in weapons technology.
 
"Biotechnology and genetic knowledge are equally open to this type of malign use.
 
"Doctors and other scientists have an important role in prevention. They have a duty to persuade politicians and international agencies such as the UN to take this threat seriously and to take action to prevent the production of such weapons."
 
Dr Nathanson warned that getting rid of weapons once they are produced is difficult.
 
"Governments may be reluctant to give up weapons that the rest of the world finds unacceptable. Terrorists certainly will be. We still have the chance to strengthen the ban on these weapons. We must do so now and we must make sure the ban is policed effectively."
 
 
Biotechnology, Weapons and Humanity traces the history of chemical and biological weapons, and highlights their potentially devastating potential for destruction.
 
On a clear, calm night, one to three million people could become infected by the release of 100 kg of anthrax spores over a major city, and the majority would die.
 
A Foreign Office spokesman said: "We would accept the threat posed by biological weapons is a very grave one.
 
"Not only is the UK one of the signatories to the international convention on biological weapons, it is arguing for that convention to be strengthened.
 
"It is the only international arms convention not to include verification regimes, and the UK believes that it should be given those teeth."





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