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Designer Drugs For Tanning,
Sex And Weight Loss Soon
Drugs Still In Trial Phases

NBC17.com
11-27-3


A synthetic hormone that's on the pharmaceutical fast track could solve your beauty and bedroom needs all at the same time.
 
"You could theoretically get tanned and have, certainly, a lot of erectile activity and you might actually start to lose weight," said Dr. Robert Dorr, a researcher at the University of Arizona.
 
The so-called Barbie drug came about when skin cancer researchers decided to test a hormone called Melanotan II on a group of men. Their hope was to stimulate a natural tan without the sun. In addition to the glowing skin the men got, they stumbled on surprising side effects -- so exciting that one researcher even tried it out on himself.
 
"After about 10 days of taking this Melanotan II, I lost about 10 pounds," Dr. Mac Hadley said.
 
"We know that it causes a short-term feeling of fullness or nausea," Dorr said.
 
Researchers say the hormone also triggers immediate sexual benefits.
 
"Even at a very low starting dose, every subject had an erection," Dorr said.
 
Several companies are developing customized drugs based on Melanotan II. Each is focused on a different benefit. An Australian lab is now testing an injection called EpiTan, which claims to produce tanned skin without any of the dangerous side effects from ultraviolet rays.
 
"It is a total duplicate of the normal tanning process in humans, except it occurs without sunlight," said Terry Winters.
 
In the United States, researchers are working on a sexual spin-off called PT-141 -- a nasal spray that promises to boost the libido in both men and women.
 
"When we give it to humans, it produces blood flow into the genitalia," said Carl Spana, with Palatin Technologies.
 
While each product will be marketed for one specific use, researchers say it's a win-win situation for patients.
 
"If taken as a sexual enhancer, it would also cause tanning if you used it frequently, and it would have the weight loss potential," Dorr said.
 
Dr. Monica Ramirez, psychologist and author of Never Good Enough, says she sees the benefits.
 
"Any pill that can help people lose weight, get a tan and improve their sex life has got to be a winner for a lot of people," Ramirez said.
 
But she worries about the ideology drugs like this would encourage.
 
"It just raises the bar. So now, everybody is expected to be thin enough, and beautiful enough, and sexy enough and it just creates a whole new way to feel like a failure," Ramirez said.
 
EpiTan has completed phase two clinical trials in Australia and is expecting Food and Drug Administration approval to begin trials in the United States by mid-2004. PT-141 has completed phase two clinical trials in the United States. It must pass a phase three pivotal trial before going on the market.
 
Copyright 2003 by NBC17.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
 
http://www.nbc17.com/health/2652603/detail.html
 

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