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Is West Nile Virus
Spread Via Aerosol?

From Dr Patricia Doyle
dr_p_doyle@hotmail.com
11-9-2

West Nile Virus update. If you notice below where it describes bird-to-bird and bird-to-human transmission, the article goes on to say that handling birds without gloves or MASK is risky.
 
Does this indicate that there is a limited aerosol risk? In other words, is the virus contracted by handling a sick bird and breathing in virus particles?
 
This would be the first time, in the history of WNV that there is even a hint of possibility of such transmission. This has NEVER been considered in previous WNV articles in the years prior to the outbreak of NY 99 isolate WNV-LIKE.
 
Another question arises, if mosquitos are not the only vector, can the virus be transmitted all year? The CDC is not really addressing these questions. They only speak of possibility and risk factors. Nothing concrete.
 
Patricia A. Doyle, PhD
 
Please visit my "Emerging Diseases" message board at:
http://www.clickitnews.com/emergingdiseases/index.shtml
 
Zhan le Devlesa tai sastimasa Go with God and in Good Health
 
----- Original Message -----
 
 
West Nile Virus Update
 
ProMED-mail promed@promed.isid.harvard.edu 11-9-2
 
ProMED-mail is a program of the International Society for Infectious Diseases http://www.isid.org
 
[There is some overlap between some of these reports, but they are reproduced on account of their different emphasis. - Mod.CP]
 
In these updates: [1] Human, imported (New Mexico ex Oklahoma) [2] Birds, direct routes of transmission [3] USDA-APHIS report (Sun 3 Nov 2002) [4] ERAP report (latest news, as of Fri 1 Nov 2002) [5] MMWR-ArboNET report (USA, 31 Oct to 6 Nov 2002)
 
******
 
[1]
 
New Mexico - San Juan County Resident Contracted West Nile Virus In Oklahoma
 
Date: Mon 4 Nov 2002 From: Marianne Hopp mjhopp12@yahoo.com Source: New Mexico Department of Health, press release, Tue 29 Oct 2002 [edited]
 
A resident of Northwestern New Mexico has been treated and released from a Stillwater Area Hospital after being diagnosed with West Nile virus infection. The 62-year-old man was fishing in Oklahoma and after feeling ill was admitted to a hospital. The man had a positive presumptive test performed by the Oklahoma Department of Health Laboratory.
 
On 22 Aug 2002, New Mexico became the 40th state to confirm the presence of West Nile virus. West Nile virus has been confirmed in 13 counties in New Mexico including Bernalillo, Curry, DeBaca, Quay, Roosevelt, Lea, Colfax, Union, Chaves, Eddy, San Miguel, Socorro, and Sandoval. "If the history of the disease in other states is an indication, if not this year, then next, we may have our first human case of West Nile Virus that originates in New Mexico," New Mexico Department of Health Secretary Jack Callaghan said. "Even though the mosquito season is slowing, in some areas of the state it is still warm. It is still important for residents to take personal precautionary steps," he added.
 
Most mosquitoes do not carry the virus and most people bitten by a mosquito have not been exposed to the virus. Less than one out of 150 people who are bitten by an infected mosquito get severely ill, according to the Centers for Disease Control and Prevention (CDC). "It is important for New Mexicans to realize that even though we have not had a confirmed positive case of West Nile virus in a human, other states have had several cases," Department of Public Health Veterinarian, Paul Ettestad said. "From the description of the case and the timing, it appears that the exposure happened while the New Mexico resident was in Oklahoma."
 
West Nile virus was first identified in the United States in New York City in 1999. According to the CDC, as of today, 3391 laboratory positive cases have been identified in humans and 188 people have died as a result of the disease. There have been no laboratory-confirmed tests in humans in New Mexico. More information is available on the New Mexico Department of Health website: www.health.state.nm.us.
 
http://www.health.state.nm.us/website.nsf/WebNavLookup/7D9B0D3259CD5B7F872566B80059E50D?OpenDocument
 
Marianne Hopp mjhopp12@yahoo.com
 
[2]
 
West Nile Virus Direct Transmission: Bird-to-Bird; Bird to Human?
 
Date: Thu 7 Nov 2002 From: A-Lan Banks a-Lan.Banks@derwent.co.uk
 
By Frank D. Roylance The Seattle Times, Wed 6 Nov 2002 [edited]
 
Ever since West Nile virus first reached the United States in 1999, health authorities have assured an anxious public that they could not get sick from contact with dead or dying birds, only from the bite of mosquitoes that carry the virus from birds to people. That's still the official word from the federal Centers for Disease Control and Prevention.
 
Although there remains no scientific proof that sick birds can infect people directly, some scientists and others who work with birds say their experiences suggest otherwise. "I think it is possible that people could get it," said Nicholas Komar, a vertebrate ecologist at the CDC. "There is plenty of virus being shed by some species of birds. When we make the statement that people are not known to be infected directly (by infected birds), it doesn't mean people can't get infected. It simply states what we know and don't know. People need to take precautions and avoid risky behavior. And handling a sick bird with bare hands and no respiratory protection is risky behavior." Health officials advise people to use precautions such as gloves, plastic bags or shovels when they handle dead birds. And natural-resources officials have urged hunters to wear gloves, to wash up carefully after cleaning or handling game, and to thoroughly cook their kill.
 
Those advisories are now being underscored. "Whether it's a virus like this or any other infection, it (West Nile) has brought back to the forefront the things people should be doing all the time," said Mark Shieldcastle, a wildlife biologist with the Ohio Department of Natural Resources. "It should be part of a hunter's daily way of life." In New York last year, a young technician was cut during a bird necropsy. Days later he was hospitalized with West Nile virus. After a second person was cut this year, the state's wildlife pathologist, Ward Stone, ordered everyone in his lab to wear stainless-steel mesh gloves sandwiched between 3 or 4 layers of latex gloves, in addition to the customary masks, face shields and gowns. It slows down their work by half. But with thousands of infected birds under the knife, and no vaccines or other treatments to rely on, Stone said "the procedures are important."
 
Although American crows have been hit hardest, birds from more than 110 species have been felled by the virus, including game species: wild ducks, Canada geese, pheasants, turkeys, pigeons, doves, and grouse. When hundreds, perhaps thousands, of owls, hawks and eagles in the Midwest fell ill with West Nile during the summer, there was speculation that they might have been infected by eating smaller birds slowed by the infection. That has not been proved; the raptors might simply have been bitten by infected mosquitoes. But there is growing evidence that West Nile virus might be spread in other ways.
 
In 2000, scientists at the National Wildlife Health Center in Madison, Wis., infected 9 crows with the West Nile virus in the laboratory. The birds were then placed in a mosquito-free flight room with 7 healthy crows. The birds all shared common food, water and perches. All the infected birds were dead 8 days later, and the previously healthy crows began to sicken and die. In a follow-up study recently submitted for publication in a scientific journal, the CDC's Komar repeated the experiment with 18 different species of birds. "We were able to document direct transmission in 4 of those," he said - American crows, black-billed magpies, blue jays and ring-billed gulls. The healthy birds began to test positive for the virus after 5 or 6 days of exposure to the infected birds. "We don't know exactly what the mode of transmission was," Komar said, "but we know it wasn't by mosquito bite." Other studies have suggested some answers. Birds that touch or feed each other, share perches, or come into contact with each other's feces might become infected that way.
 
http://seattletimes.nwsource.com/html/healthscience/134570125_westnile06.html -- Banks, A-Lan a-Lan.Banks@derwent.co.uk
 
****** [3]
 
Equine Cases of West Nile Virus Illness in 2002: 1 Jan to 3 Nov 2002
 
Date: Wed 6 Nov 2002 From: ProMED-mail promed@promedmail.org Source: United States Department of Agriculture, Animal and Plant Inspection Service, Update on the Current Status of West Nile Virus, as of Sun 3 Nov 2002 [edited]
 
The total number of equine cases of illness caused by West Nile virus (WNV) confirmed at the USDA's National Veterinary Services Laboratories (NVSL) or reported by state officials so far this year is 12 843. That is an increase of 886 cases from one week ago.
 
The cases are from 39 states: Alabama (88), Arkansas (131), Colorado (378), Connecticut (1), Delaware (8), Florida (315), Georgia (50), Idaho (1), Illinois (949), Indiana (688), Iowa (1,039), Kansas (629), Kentucky (499), Louisiana (358), Maryland (16), Massachusetts (2), Michigan (342), Minnesota (964), Mississippi (256), Missouri (681), Montana (134), Nebraska (1,096), New Jersey (45), New Mexico (61), New York (28), North Carolina (11), North Dakota (569), Ohio (636), Oklahoma (733), Pennsylvania (79), South Carolina (7), South Dakota (671), Tennessee (124), Texas (986), Vermont (3), Virginia (42), West Virginia (3), Wisconsin (127), and Wyoming (93).
 
http://www.aphis.usda.gov/oa/wnv/wnvstats.html
 
****** [4]
 
West Nile Virus Latest News - as of Fri 1 Nov 2002
 
Date Sat 2 Nov 2002 From: ProMED-mail promed@promedmail.org Source: Environmental Risk Analysis Program, Cornell University Center for the Environment, Fri 1 Nov 2002 [edited]
 
In 2002 West Nile virus (WNV) has been detected in 43 states across the US and 5 provinces in Canada, from Saskatchewan to Nova Scotia. In the US the only states where it has not been detected are Alaska, Arizona (several cases imported from elsewhere), Hawaii, Idaho (though detected in a raven in a bordering county in Washington), Nevada, Oregon (human case contracted elsewhere) and Utah. In many states WNV has been detected in all, or nearly all, counties, including several on the Mexican border. [The remainder of the report is superceded by the MMWR report below].
 
http://www.cfe.cornell.edu/erap/WNV/
 
****** [5]
 
West Nile Virus Activity - United States, Thu 31 Oct to Wed 6 Nov 2002
 
Date: Thu 7 Nov 2002 From: ProMED-mail promed@promedmail.org Source: Morbidity and Mortality Weekly, West Nile Virus Activity, Fri 8 Nov 2002, 51(44);999-1000 [edited]
 
This report summarizes West Nile virus (WNV) surveillance data reported to CDC through ArboNET and by states and other jurisdictions as of Wed 6 Nov 2002.
 
During the period Thu 31 Oct to Wed 6 Nov 2002, a total of 88 laboratory-positive human cases of WNV-associated illness were reported from Ohio (n=28), Michigan (n=11), Kentucky (n=8), Oklahoma (n=8), Texas (n=8), Georgia (n=5), Louisiana (n=4), Iowa (n=3), Missouri (n=3), Florida (n=2), Wisconsin (n=2), Tennessee (n=2), Maryland (n=one), Massachusetts (n=one), Minnesota (n=one), and New York (n=one).
 
During the same period, WNV infections were reported in 219 dead crows and 93 other dead birds. A total of 810 veterinary cases and 45 WNV-positive mosquito pools were reported.
 
During 2002, a total of 3507 human cases with laboratory evidence of recent WNV infection have been reported from Illinois (n=719), Michigan (n=483), Ohio (n=413), Louisiana (n=321), Indiana (n=247), Mississippi (n=182), Missouri (n=165), Texas (n=148), Nebraska (n=115), New York (n=74), Kentucky (n=67), Pennsylvania (n=59), Tennessee (n=52), Iowa (n=48), Minnesota (n=42), Alabama (n=41), Wisconsin (n=39), South Dakota (n=37), Georgia (n=30), the District of Columbia (n=27), Maryland (n=25), Virginia (n=24), Massachusetts (n=22), Arkansas (n=21), Florida (n=18), Connecticut (n=17), North Dakota (n=17), Oklahoma (n=16), New Jersey (n=11), Colorado (n=10), Kansas (n=6), West Virginia (n=3), North Carolina (n=2), California (n=one), Delaware (n=one), Rhode Island (n=one), South Carolina (n=one), Vermont (n=one), and Wyoming (n=one).
 
Among the 3148 patients for whom data were available, the median age was 56 years (range: 1 month to 99 years); 1676 (54 percent) were male, and the dates of illness onset ranged from 10 Jun to 19 Oct 2002. A total of 187 human deaths have been reported. The median age of decedents was 78 years (range: 24 to 99 years); 111 (59 percent) deaths were among men.
 
In addition, 7312 dead crows and 5436 other dead birds with WNV infection were reported from 42 states and the District of Columbia; 8143 WNV infections in mammals (8130 equines, 3 canines, and 10 other species) have been reported from 36 states (Alabama, Arkansas, Colorado, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maryland, Massachusetts, Minnesota, Mississippi, Missouri, Montana, Nebraska, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Vermont, Virginia, Wisconsin, and Wyoming).
 
During 2002, WNV seroconversions have been reported in 366 sentinel chicken flocks from Florida, Iowa, Nebraska, North Carolina, Pennsylvania, Texas, and New York City; 4827 WNV-positive mosquito pools have been reported from 27 states (Alabama, Arkansas, Connecticut, Delaware, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Maryland, Massachusetts, Mississippi, Missouri, Nebraska, New Hampshire, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Rhode Island, South Carolina, South Dakota, Texas, Vermont, and Virginia), New York City, and the District of Columbia.
 
Additional information about WNV activity is available at: http://www.cdc.gov/ncidod/dvbid/westnile/index.htm and http://www.cindi.usgs.gov/hazard/event/west_nile/west_nile.html
 
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5144a5.htm
 
ProMED-mail promed@promedmail.org





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