- (HealthScoutNews)-- The humble spud may stand poised
for a major medical breakthrough.
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- A patented starchy powder made from potatoes appears
to clot blood instantly. That could come in handy during surgeries and
emergency procedures and also reduce the number of blood transfusions,
say Mayo Clinic researchers who presented their findings today at the American
Society of Anesthesiologists' annual meeting in Orlando, Fla.
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- "It works like a sponge for water molecules in the
blood, allowing the platelets to clot almost immediately," says lead
researcher Dr. Mark H. Ereth, an associate professor of anesthesiology
at the Mayo Clinic.
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- The powder, approved for most surgical uses in the United
States, Canada and Europe, sidesteps problems associated with other clotting
agents. It is cheaper and cleaner than clotting agents made from human
and cow plasma, and it avoids the risks of disease and allergic reaction,
Ereth says.
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- "The stuff that's out there doesn't work well enough,
which is why we're looking for something better," adds Dr. Gregory
Nuttall, a secondary author of the paper.
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- In their study, the researchers made two tiny incisions
in the arms of 30 people. One incision was treated with the potato powder;
the other was left to clot on its own. The untreated cut took almost six
minutes to reach hemostasis -- which is when blood clots -- while 77 percent
of the cuts treated with the powder stopped bleeding immediately.
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- "In the other 23 percent of cases, the clotting
was rapid, but there was a little bit of oozing afterward," Ereth
says.
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- Dr. Linda Stehling, who chairs the American Society of
Anesthesiologists' transfusion committee, says, "I'm impressed by
the numbers. This could take care of real and theoretical concerns about
using human and bovine plasma."
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- Stehling says she's waiting to see how the agent holds
up under more complex trials and how applicable it becomes in general practice.
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- The study was funded by Medafor Inc., of Minneapolis,
which manufactures the porous starch and holds the patent on the process
to make it. The Mayo Clinic has tested the agent for about two years, with
prior trials on animals, Ereth says.
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- The powder, which is made of purified potato starch processed
to produce tiny, absorbent particles, can help surgeons avoid blood transfusions
by preventing excessive bleeding. It's particularly useful for paramedics
or combat doctors who must stabilize massive wounds before the onset of
trauma from loss of blood, Ereth says.
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- In routine surgical operations, avoiding transfusions
saves money and prevents possible disease transmission and serious allergic
reactions. The starch also breaks down quickly in the body, unlike other
clotting agents, Ereth says.
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- All of that from a potato.
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- "I think a lot of times we go looking for very complex
solutions. But sometimes elegance is in simplicity," Ereth says.
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