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Four Blood Recipients
Test Positive For West Nile

9-12-2

ATLANTA (Reuters) - Four people who recently received blood transfusions have tested positive for the potentially fatal mosquito-borne West Nile virus, U.S. health officials reported on Thursday.
 
 
The U.S. Centers for Disease Control and Prevention and the Food and Drug Administration said the blood products given to the victims had been withdrawn as a precaution, though they stressed that there was no evidence linking the West Nile infections to the nation's blood supply.
 
Dr. Lyle Petersen, a West Nile expert with the CDC, said the two federal agencies were cooperating with the American Red Cross and state and local health departments to follow up and test those who had donated blood to the four patients.
 
There have been 1,201 human cases of West Nile in the United States this summer, including 46 deaths. The outbreak is the largest since West Nile, which is common in Africa and the Middle East, surfaced in the Americas three years ago.
 
"By chance alone, some of these persons will have received blood transfusions," said Petersen, who noted that all four of the cases involving blood transfusions had occurred in areas where the mosquitoes that spread West Nile virus were active.
 
"Recent receipt of a blood transfusion by a person with West Nile virus infection does not necessarily implicate the transfusion as the source of infection," Petersen said.
 
Fears that West Nile, which can cause encephalitis, a severe brain inflammation, could be transmitted through blood surfaced earlier this month after four organ recipients were infected from a single donor in Georgia.
 
Tens of thousands of Americans may have been exposed to the virus since it first appeared in the United States in 1999, when it killed seven people in the New York borough of Queens.
 
 
 
Although most people bitten by a West Nile-carrying mosquito have no symptoms and those who do normally suffer little more than flu-like illness, they can still carry the virus in their blood for days or even weeks.
 
Although health officials concede that they do not currently have the capability to test the nation's blood supplies for the virus, they said the potential risk of contracting West Nile from blood was likely very small.
 
"For the overwhelming majority of people, even if West Nile is a problem the blood that they get is extremely safe and offers no problem," said Dr. Jesse Goodman, deputy director of the FDA's Center for Biologics, Evaluation and Research.
 
Goodman, however, said excluding some donors from giving blood might be among the options considered if West Nile became a threat to the blood supply.
 
While federal agencies grapple with the issue of blood transmission of West Nile, state and local health officials continue to battle the virus as it approaches its seasonal peak in mid-September.
 
Although initially centered in the Southern states of Louisiana, Mississippi and Texas, this year's outbreak has moved into the Midwest with a vengeance. States such as Illinois and Michigan have been particularly hard hit.
 
Illinois has reported 292 human cases of West Nile, the most in the nation, according to the CDC.
 
At least 42 states, stretching from Maine to California, and the District of Columbia have reported some West Nile activity this year. The virus, which is spread largely through bird migrations, has also been detected in parts of Canada.
 
Mosquitoes contract West Nile from infected birds and then spread it to humans. The virus cannot be spread from person to person or from birds to humans.
 
 
Copyright © 2002 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.





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