-
- An Aug 3 news release said research is to be carried
out on whether there are possible links between aspartame and brain cancer.
This is to be headed by neurochemist Dr. Peter Nunn of Kings College in
London.
-
- Monsanto (NutraSweet) says: "It is physiologically
impossible for aspartame to cause brain tumors because it never enters
the bloodstream and thus cannot travel to essential organs, including the
brain."
-
- Aspartame is a molecule composed of three components,
aspartic acid, methanol and phenylalanine. H. J. Roberts, M.D., says in
Aspartame (NutraSweet) Is It Safe?
-
- Page 30: "After ingestion there is a rapid breakdown
and absorption of aspartame within the upper gastrointestinal tract. This
results in a prompt rise of the two amino acids in the bloodstream."
-
- Page 32: "Influence of Method of Administration"
Both phenylalanine and aspartame concentrations in the blood plasma are
significantly higher when aspartame is given as a solution rather than
in capsule form."
-
- Aspartame, Physiology and Biochemistry, Marcel Dekker,
Inc., New York, L.D. Stegink and L. J. Filer, Jr., l984 (Pro industry,
Significantly Corporate Sponsored!! ) Searle was original manufacturer,
bought by Monsanto in l985
-
- Page 161: TISSUE DISTRIBUTION OF ORALLY ADMINISTERED
ISOTOPICALLY LABELED ASPARTAME IN THE RAT Yoshimasa Matsuzawa and Yuichi
O'Hara, Life Science Laboratory, Central Research Laboratories, Ajinomoto
Company, Inc. Yokohama, Japan
-
- Page 162: RESULTS: Phenylalanine Moiety: "The
pattern of distribution of (U-14CPhe) aspartame following its oral administration
was very similar to that of (U-14C) phenylalanine after 0.5, 2.6 and 24
hr and 7 days. Thirty minutes after administration of these compounds,
very high levels of radioactivity were observed in the lumen of the stomach
and upper small bowel. Significant uptake of radioactivity was observed
in the pancreas, gastrointestinal mucosa, hair follicles, salivary gland
and liver. Radioactivity was observed in the kidney, adrenal gland, bone
marrow, spleen and eye. Some radiolabel was localized to the BRAIN, SPINAL
CORD, (emphasis added) heart, thymus, lung and testes.
-
-
- In real world demographic studies that could be dated
from July, l981 when aspartame became commercially available, Dr. Roberts
in DOES ASPARTAME CAUSE HUMAN BRAIN CANCER?, Journal of Advancement in
Medicine, Volume 4, Number 4, Winter 1991, emphasized the extraordinary
rise of primary brain lymphoma in persons who were not immunosuppressed
within one or two years after the availability of aspartame products. --
and for which no other reasonable cause could be identified. Primary brain
lymphoma had been a rare brain tumor prior to that time; subsequently there
was a striking rise of other more common primary brain tumors within several
years after the availability of aspartame in soft drinks and other products,
beginning July, l983. These data on brain cancer statistics were regarded
by the American Cancer Society statisticians as significant, and for which
no other cause was apparent. Dr. Roberts report was a milestone publication,
presented 15 years after the previous demonstration of high incidence of
brain tumors in rats given aspartame. Indeed, these experimental studies
were the reason that FDA scientists, consultants for the GAO, and a Public
Board of Inquiry had urged the FDA Commissioner NOT TO APPROVE aspartame
for human use. Unfortunately, a new FDA Commissioner ignored these warnings.
In subsequent letters and books by Dr. Roberts, including a communication
published in Lancet, Vol. 349, Feb 1, l997, Roberts reemphasized the matter,
and urged the FDA to declare aspartame products an imminent public health
threat for their potential carcinogenic, neurologic,psychiatric, metabolic
and fetotoxic potential based on a clinical database now exceeding 1300
aspartame reactors.
-
- As further refutation of assertions by the manufacturer,
and the FDA that there are no evidences for severe neurotoxicity, Dr. Roberts
and others have listed and reviewed many reports to the contrary -- with
emphasis on corporate - neutral studies involving "real world"
products subjected to heat and storage. Even corporate - sponsored studies
affirmed the matter. For example, one of 15 pivotal studies submitted to
the FDA for approval of aspartame was a "52 Week Oral Toxicity Infant
Monkey Study (SC-18862). This study orally dosed aspartame to seven infant
Rhesus monkeys in work conducted at the University of Wisconsin Medical
Center at Madison. Reported in l972. The study reported "All animals
in the medium and high dosage groups exhibited seizure activity. Seizures
were observed for the first time following 218 days of treatment. The
seizures were of the grand mal type.. One monkey, m38 of the high dose
group, died after 300 days of treatment. The cause of death was not determined
.." The study correlates brain seizures with high amounts of phenylalanine
ingested by the monkeys. The study determined: "following the end
of the experiment, medium and high dose monkeys were kept under observation
for three months. No further convulsions were detected during this period."
In other words, once the aspartame was withdrawn from the monkey's diets,
the brain seizures ceased. Monsanto spokesperson Dr. Robert Moser has said
that aspartame does not enter the blood stream. The data revealed by this
"pivotal" study submitted to FDA renders false Moser's assertion
that Aspartame does not enter the blood stream. Elevated levels of phenylalanine
in the blood of monkeys fed medium and high levels of Aspartame prove that
the compound is absorbed into the blood stream. The brain seizures followed.
How could FDA claim a "pivotal " study in which all of the medium
and high dose monkeys suffer brain seizures, confirm Aspartame's safety
for humans?
-
- Neurosurgeon Russell Blaylock, M.D. in Excitotoxins:
The Taste That Kills explains that for every molecule of aspartame metabolized,
a molecule of methanol was released into the blood stream. An EPA assessment
of methanol states that methanol "is considered a cumulative poison
due to the low rate of excretion once it is absorbed" The absorbed
methanol is then slowly converted to formaldehyde by alcohol dehydrogenase
in the liver (DHHS 1993a, Liesivuori 1991). The formaldehyde is then converted
to formic acid by aldehyde dehydrogenase in the liver, by formaldehyde
dehydrogenase in the blood or through the tetrahydrofolic acid dependent,
one-carbon pool (Liesivuori 1991). Methanol thus breaks down into formaldehyde
and formic acid in the body. Journal of the Diabetic Assoc. of India,
A Health Alert, Emerging Facts About Aspartame, Vol. No. 35, No. 4: l995,
J. Barua, A. Bal
-
- During Congressional Hearings on aspartame there was
voluntary submission of Trade Secret Information, Document 31. This had
to do with Food and Drug Sweetener Strategy on getting aspartame approved
and says in the last paragraph: "With the spoon-for-spoon, we have
no way of estimating maximum likely abuse and hence need to utilize data
based on almost complete conversion to DKP. If we include this use in
the original FAP, we stand a good chance of ending up with nothing in the
short run and nothing in the long run whereas the other approach would
give us something in the short run and quite likely as much as we would
ever get in the long run." ..
-
- DKP is diketopiperazine and has been implicated in the
occurrence of brain tumors. Dr. John Olney, noticed that DKP, when nitrosated
in the gut, produced a compound which was similar to N-nitrosourea, a powerful
brain tumor causing chemical.
-
- What is so serious about this situation is that Searle
knew before they marketed aspartame that the phenylalanine would break
down to DKP, and they didn't think they could get it approved if the FDA
found out. Indeed, rats developed brain tumors in original studies. An
FDA toxicologist who tried to stop the approval of aspartame, the late
Dr. Adrian Gross, told Congress that because aspartame was capable of producing
brain tumors and brain cancer, FDA should not have been able to set an
allowable daily intake of the substance at any level. He said at least
one of Searle's studies "has established beyond any reasonable doubt
that aspartame is capable of inducing brain tumors in experimental animals
and that this predisposition of it is extremely of high significance..In
view of these indications that the cancer causing potential of aspartame
is a matter that had been established way beyond any reasonable doubt,
one can ask: What is the reason for the apparent refusal by the FDA to
invoke for this food additive the so-called Delaney Amendment to the Food,
Drug and Cosmetic Act?" The Delaney Amendment makes it illegal to
allow any residues of cancer causing chemicals in foods. The concluding
testimony of Dr. Gross will never be forgotten. He asked: "Given
the cancer causing potential of aspartame, how would the FDA justify its
position that it views a certain amount of aspartame as constituting an
allowable daily intake or 'safe" level of it? Is that position in
effect not equivalent to setting a 'tolerance' for this food additive and
thus a violation of that law? And IF THE FDA ITSELF ELECTS TO VIOLATE
THE LAW, WHO IS LEFT TO PROTECT THE HEALTH OF THE PUBLIC?" (Emphasis
added). Congressional Record SID835:131 (August 1, l985)
-
- In Nov l996 John W. Olney, M.D, reported that brain tumor
rates had risen for 17 years with a sudden 10% increase three years after
aspartame was introduced. Olney linked aspartame's mutagenicity to the
function of aspartate as an excitotoxic neurotransmitter. Dr. Olney appeared
on 60 Minutes and with him Dr. Ralph Walton who declared that only NutraSweet
funded studies showed safety and that 83 of 90 independent studies show
it harmful. This year world famous toxicologist, George Schwartz, M.D.,
in writing to Monsanto said: "By ignoring the scientific studies which
disagree with your position, you are doing a great disservice to consumers.
Further, you may have created base for litigation against your company
by denying the existing science." (letter on www.dorway.com)
-
- Dr. H. J. Roberts has now declared Aspartame Disease
to be a world epidemic and is in the process of publishing a 700 page medical
text on the world plague.
-
- Suggested documents to review:
-
- FDA audit, Bressler Report CDC Investigation Protest
of National Soft Drink Association
-
- Letters from Dr. Adrian Gross to Senator Metzenbaum
-
- Affidavit from N. Vera,translator, that studies were
done in South America on humans that showed aspartame triggered brain
tumors and seizures, and were never published by Searle.
-
- These documents on www.dorway.com
-
- Betty Martini, Founder
- Mission Possible International
- 9270 River Club Parkway
- Duluth, Georgia 30097
- 770 242-2599
-
- Mission Possible Intl is a worldwide volunteer force
alerting consumers
- aspartame is a neurotoxin. Two support groups have been
set up on the
- Internet for the victims of Aspartame Disease.
-
-
- The important thing is in intact human beings who are
exposed to this on a
- sustained level, not just with just a couple of doses
or so , its
- cumulative. (Said by H. J. Roberts, M.D.)
-
- *******************************
-
- 1. Take the 60-day No Aspartame Test and send us your
case history.
- Mission Possible International
- 9270 River Club Parkway
- Duluth, GA 30097 USA
- 770-242-2599
-
- 2. Tell your doctor and all of your friends!
-
- 3. Return Asparcidal food to the store.
- (anything with Monsanto's NutraSweet/Equal/Spoonful/Benevia/NatraTaste)
-
- VISIT http://www.dorway.com Get links to over 200 sites
on aspartame
- VISIT http://www.holisticmed.com/aspartame/ FAQs &
Cases
- VISIT http://www.notmilk.com Exposing Bovine Growth Hormone
- VISIT http://www.icanect.net/sunpress/ Books on aspartame
by Dr. Roberts
-
- Disability and Death are not acceptable costs of business!
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