| Abstract
The TSE’S or transmissible spongiform encephalopathies, include bovine
spongiform encephalopathy (also called BSE or “mad cow disease”), CreutzfeldtJakob
disease (CJD) in humans, and “scrapie” in sheep or goats (caprinespongiform
encephalopathy). They remain a mystery, their cause still hotly
debated. Current mad cow diagnosislies solely in the detection of late
appearing “prions”, an acronym for hypothesized, geneless, misfolded proteins,
somehow claimed to cause the disease. Yet laboratory preparations of prions
contain other things, which could include unidentified bacteria or viruses.
And the only real evidence that prion originator Stanley Prusiner had
in hisoriginal paper that the disease agent behind “Scrapie” in sheep
and goats was devoid of DNA or RNA wasbased upon the fact that he couldn’t
find any. Furthermore, the rigors of prion purification alone, might,
in and ofthemselves, have killed any causative microorganism and Heino
Dringer, who did pioneer work on their nature,candidly predicts “it will
turn out that the prion concept is wrong.” Roels and Walravens as well
as Hartly tracedMad Cow to Mycobacterium bovis. Moreover, epidemiologic
maps of the origins and peak incidence of Mad Cowin the UK, suggestively
match those of England’s areas of highest bovine tuberculosis, the Southwest.
Theneurotaxic potential of bovine tuberculosis has for some time been
well known. By 1911 Alois Alzheimer calledattention to “a characteristic
condition of the cortical tissue which Fischer referred to as ‘spongy
cortical wasting”in Alzheimer’s disease (AD). But behind AD, Fischer suspected
a microbe called Streptothrix which wasconstantly being mistaken and confused
for tuberculosis. Our present investigation of the TSEs clearly shows
cell-wall-deficient (CWD) tubercular mycobacteria present, verified by
molecular analysis, ELISA, PCR and microscopy to cause spongiform encephalopathy.
Keywords: Prions; Scrapie; The Spongiform Encephalopathies; Alzheimer’s
disease; The etiology of Alzheimer’s Disease; Mycobacterium tuberculosis
Complex
Received: April 05, 2017; Accepted: April 27, 2017; Published: April 29,
2017
CWD Tuberculosis Found in Spongiform Disease Formerly
Attributed to Prions: Its Implication towards Mad Cow Disease, Scrapie
and Alzheimer’s (PDF) |
