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Acute Flaccid Paralysis Outbreak In Germany |
| From
Patricia Doyle PhD |
| Hello Jeff - if you remember during the invasion of the 'unaccompanied
youth' into the US from 2012 to 2014, California also had cases of acute
flaccid paralysis. Probably brought here by illegals who get no health
checkups. Of course, we never head any further info on the acute flaccid paralysis in California and the illegals were dispersed all over the country. They were all infected with scabies and other diseases including measles and mumps. The disease situation for Europe and the US is quite serious. As soon as these savages go home they should be refused re-entry into the US or Europe. They are NOT refugees or 'asylum seekers.' if they go home to visit and are not harmed, that proves the case. They are no longer in need of asylum. They also do not need welfare or support. Time to send them ALL home and tell them that there are real asylum seekers who do need asylum. Like white South Africans who are being murdered practically every day of the week. Patty GERMANY ACUTE FLACCID PARALYSIS Published Date: 2017-09-12 22:21:40 Subject: PRO/EDR> Acute flaccid myelitis - Europe: Germany Archive Number: 20170912.5311829 ACUTE FLACCID MYELITIS - EUROPE: GERMANY ****************************************** A ProMED-mail post http://www.promedmail.org ProMED-mail is a program of the International Society for Infectious Diseases http://www.isid.org Date: Fri 8 Sep 2017 Source: News Medical Net, aerzteblatt.de report [edited] https://www.news-medical.net/news/20170908/Severe-cases-of-polio-like-illness-observed-among-children-in-many-countries.aspx In Germany in the summer and autumn of 2016, several cases of illness in children were observed that were accompanied by acute flaccid paralysis. For the entire year 2016, 16 of such polio-like cases were registered with the Robert Koch-Institute. In an article in the current issue of Deutsches Arzteblatt International (Dtsch Arztebl Int 2017; 114 (33-34): 551-557), Johannes Hubner et al. describe this disease on the basis of 2 case reports, in which the neurological symptoms ranged from flaccid paralysis of the arm to tetraplegia requiring intubation and ventilation. In the children under study, the main characteristic was damage to the anterior horn of the spinal cord as confirmed on MRI or lesions as a sign of motor neuron injury as confirmed electrophysiologically. A pathogen could almost never be detected in cerebrospinal fluid, but epidemiological associations and confirmation of viruses from stool specimens or respiratory secretions pointed at enteroviruses as the likely pathogen. The prognosis of such polio-like disease with flaccid paralysis of differing severity cannot be estimated at the beginning--it ranges from hardly detectable impairment of the arm movement to care dependency in permanent severe symptoms. Targeted therapeutic measures are not available. No sufficient evidence currently exists for the effectiveness of corticosteroids, immunoglobulins, plasmapheresis, or antiviral medications. The authors express concern that since 2012, several cases of severe flaccid paralysis have been observed in several countries, which closely resemble the symptoms of poliomyelitis, but which are caused by different pathogens that are often not identifiable. The term "acute flaccid paralysis with anterior myelitis" has been adopted, in order to distinguish the symptoms from those of classic poliomyelitis. Conclusions from Hubner et al.: "Polio-like courses of acute encephalitis with flaccid paralysis in children have been described in many European countries and in the US in recent years. Epidemiological associations indicate that these conditions are caused by enteroviruses, even though CSF testing for pathogens tends to return negative results in almost all cases. More frequently, it is possible to detect pathogens in stool or respiratory secretions, but this does not prove a pathogenetic relationship. Other causes (bacterial or viral infections) and Guillain-Barre syndrome must be ruled out. The characteristic MRI pattern plays an important role in the differential diagnosis of the condition. " -more... -- Communicated by: ProMED-mail <promed@promedmail.org> [See Dtsch Arztebl Int paper cited above for figures and further discussion, as well as earlier ProMED posts on acute flaccid paralysis in North America. "Although AFP with anterior myelitis or grey matter involvement (i.e., evidence of inflammation of the spinal cord involving the grey matter including anterior horn cell bodies) comprises a subset of patients with AFP, these cases can be challenging to distinguish at initial presentation before clinical, imaging, and laboratory study results are available. Thus, specimen collection to definitively rule out poliovirus infection from possible differential diagnoses should be considered among all patients with AFP of unknown etiology or a suspected viral etiology. This is particularly important for persons who are unimmunized and have a history of travel to countries with endemic polio or countries that use OPV for routine immunization. "Physicians treating patients with AFP of unknown etiology should work with their local and state health departments to rule out poliomyelitis early during the course of disease. To ensure adequate specimens for poliovirus testing, specimens should be collected according to CDC and WHO guidelines. "Epidemiologic and laboratory investigation did not identify poliovirus infection as a possible cause for the observed cases. No common etiology was identified to explain the reported cases, although EV-D68 was identified in upper respiratory tract specimens of 2 patients. EV infection, including poliovirus infection, should be considered in the differential diagnosis in cases of AFP with anterior myelitis and testing performed per CDC guidelines. "Common features among the clinical presentations of patients included an upper respiratory or gastrointestinal prodrome less than 10 days before AFP onset (83 percent), CSF pleocytosis (83 percent), and absence of sensory deficits (78 percent) ". -more... The text above is excerpted from Ayscue P, Van Haren K, Sheriff H, et al. Acute Flaccid Paralysis with Anterior Myelitis -- California, June 2012-June 2014. 2014. 63(40);903-6. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6340a6.htm. The authors evaluated 23 cases of acute flaccid paralysis (AFP) associated with anterior myelitis. A healthmap/ProMED of Germany can be found at http://healthmap.org/promed/p/101. - Mod.LK] See Also dated May 12, 2017 Syria CIDRAP Investigators probe acute flaccid paralysis cluster in Syria Health officials are investigating a cluster of 23 acute flaccid paralysis cases in Syria, and test results on one of the samples suggests potential vaccine-derived poliovirus (VDPV), ProMED Mail reported on May 12, based on a submission from an anonymous source that it says is known and reliable. Samples were apparently sent to the US Centers for Disease Control and Prevention (CDC) for further testing. Authorities are worried that the virus is a circulating VDPV (cVDPV) type 2. The case cluster is located in the Miadin district of Deir ez-Zor governorate in eastern Syria. ProMED said the submission is the first validation of media reports describing a suspected polio case cluster, adding that there is instability in the area, which experienced a wild poliovirus outbreak in 2013 that at the time prompted vaccination campaigns. ProMED said lower routine vaccine coverage heightens the prospect of cVDPV in inadequately vaccinated people. So far this year, only five wild poliovirus cases have been reported—three in Afghanistan and two in Pakistan. No cVDPV cases have been recorded so far, compared with three at this time last year, according to the latest information from the Global Polio Eradication Initiative (GPEI). May 12 ProMED Mail post GPEI polio case update |