- The year was 1921. America was entering a decade of robust
prosperity. Later called "The Roaring Twenties", it was a time
of unparalleled economic expansion. Debt money from Wall Street banks was
plentiful and easy to obtain. The "Great War" was over.
-
- America was flexing her industrial muscles. Factories
were being built and expanded in every major city. Automobiles began rolling
off Detroit assembly lines in record numbers. The stock market began making
millionaires. People were HEALTHY and HAPPY largely because the dreaded
"world mystery disease" (which decades later became known as
the "1918 Flu Pandemic") had disappeared. Two entire years had
passed with no dreaded "mystery deaths" being reported. America
had cause to celebrate, and celebrate they did!
-
- As a matter of fact, the American Public in general was
so optimistic and HAPPY in 1921, that relatively few people were unhealthy
as well. For the first time in decades, hospital beds were empty. The fledgling
American Medical Association, formed by John D. Rockefeller just a few
years earlier, was worried. Business was sagging.
-
- Profits from vaccines and drugs were spiraling. Something
had to be done, and done immediately. False, faux epidemics of smallpox
were created to solve the problem, and keep the Medical Mafia's cash registers
ringing.
-
- We know this dastardly plan actually happened, thanks
to a citizen's WATCHDOG GROUP in Kansas City, Missouri named "The
Advertiser's Protective Bureau", who filed, and successfully prosecuted
criminal charges against the Missouri state chapter of the AMA the
Jackson Medical Society. The 'Protective Bureau's" official report
of this cold-blooded plot reads as follows:
-
- "In the Fall of 1921, the health of the city was
unusually good, but slow for the doctors. So the Jackson Medical Society
met and resolved to make an epidemic in the city. According to the minutes
of this meeting: 'MOTION WAS MADE AND SECONDED, THAT A RECOMMENDATION BE
MADE BY THE COMMITTEE, TO THE BOARD OF HEALTH, THAT AN EPIDEMIC OF SMALLPOX
BE DECLARED IN THE CITY. (Investigation later revealed that there was NO
SIGN OF AN EPIDEMIC at the time, in the city, or anywhere in the state
or region!)
-
- 'It was moved and seconded that a day be set aside, termed
VACCINATION DAY, on which physicians would be stationed at ALL SCHOOLS,
clinics, public buildings and hospitals to vaccinate "free of charge".
(Vaccinations are never "free". The taxpayers are always forced
to pay for every one of the "free" vaccines.)
-
- "IT IS FURTHER RECOMMENDED THAT WIDE PUBLICITY BE
GIVEN, STATING THAT VACCINATION IS A PREVENTIVE OF SMALLPOX, AND URGING
THE ABSOLUTE NECESSITY OF VACCINATION FOR EVERY MAN, WOMAN, AND CHILD IN
THE CITY."
-
- The Protective Bureau proved in court that there WAS
NO EPIDEMIC before the vaccinations!! The court records show that the Medical
Society manufactured vast amounts of posters, fliers, newspaper stories
and ads featuring horrific and lurid pictures of diseased children covered
with massive smallpox sores and open wounds. Some pictures actually showed
children's corpses covered with the same ugly sores. The PANIC-DRIVEN message
was clear --- VACCINATE EVERYONE, or face a deadly public disease. There
was a "sweeping epidemic" in the city; the disease was "highly
contagious" and would "strike anyone who was not vaccinated"
was the bill of goods sold! (Does this sound at all familiar today
88 years later??)
-
- The Medical Mafia's propaganda blitz was successful,
and over a million previously healthy and happy American citizens were
hypnotized and terrorized into placing the vaccine toxins into their bloodstreams.
All public school children in the region were vaccinated while at school!
Parents who dared question the vaccination of their children were ostracized
and publicly vilified.
-
- THE COURT RECORD ON THIS CASE IS VERY CLEAR. In the weeks
and months following the "mass vaccinations" the area's
hospital beds were filled to over-flowing with VACCINE-INDUCED SMALLPOX
CASES!
-
- Tens of thousands of people became ill, and many hundreds
of innocents died, and many more were permanently crippled! Of course,
THE NEWSPAPERS THEN TRUMPETED HOW WISE THE MEDICAL ESTABLISHMENT WAS TO
PROMOTE THE VACCINES stating how much worse the death toll would
have been without the vaccination campaign!! Untold MILLIONS OF DOLLARS
of profit was generated by this massive "medical" fraud.
-
- Thanks to the ADVERTISER'S PROTECTIVE BUREAU, however;
the massive fraud was exposed and criminally prosecuted to a successful
conviction. During the trial, three amazing facts were proven beyond any
"reasonable doubt".
-
- Fact 1: The poster and advertising pictures showing the
diseased and dying children used so successfully by the "doctors",
WERE NOT EVEN CASES OF LOCAL SMALLPOX CASES AS THEY WERE BILLED TO BE!
The Protective Bureau documented that they were pictures of ENGLISH CHILDREN
who were victims of "court-proven" cases of SMALLPOX VACCINE
POISONING!! One of the pictures was of a 5-week-old baby named Mona Stevenson,
of Humphrey Street, Burnley, England. A previously healthy and happy baby,
Little Mona had been vaccinated for smallpox at 5 weeks of age. Four weeks
later, her pox-ridden little body was placed in a tiny coffin and buried.
The horrific photos of Little Mona and others in England had previously
been published in British newspapers where details of the resulting CRIMINAL
TRIALS were also given. The full details of the trials, as well as the
pictures, were also included in a comprehensively large medical boot titled
"THE HISTORY AND PATHOLOGY OF VACCINATION" by Edgar M Crookshank,
MD professor of Bacteriology at the ultra-elite Kings College, London
England.
-
- Fact 2: Vaccines containing LIVE VIRUSES, weakened (i.e.
attenuated) or otherwise universally causes more diseases than the vaccine
ever could prevent.
-
- Fact 3: Vaccine-Induced-Disease (VID) is an extremely
effective socio-economic tool. It has the potential to generate BILLIONS
OF DOLLARS OF WINDFALL PROFITS, while permanently changing the social structures
of large groups of people.
-
- While the Protective Bureau won the criminal court case
the American People lost. The case should have made front-page headlines
around the nation, showing the Modus Operandi of certain corrupt "medical
practitioners". How, by means of fraud, treachery, and trickery, they
made millions of dollars in windfall profits while thousands of innocent,
trusting, and naïve Americans suffered and died. The entire sordid
affair, with all its damning details, was kept out of the American Press.
John D. Rockefeller's AMA, with its millions of dollars of influence
made sure of that!
-
- Amazingly, even though thousands of people had died or
become crippled by this managed manslaughter, the doctors involved were
only given a light penalty in the form of a token fine. The medical establishment
as a whole was not upset in the least by the exposure and has continued
on unabated perpetuating the same crimes against humanity creating
vaccine-induced-diseases while fleecing the people continually until this
present day.
-
- It is a proven (albeit little-known) fact, EPIDEMIC/PANDEMIC
MANUFACTURING IS STANDARD PRACTICE with the world-wide "Medical Mafia"
circles. In order to maximize profits and re-shape geographical regions,
they often manufacture a false-flag "emergency". If there is
an outbreak of mild seasonal virus, they call it an influenza pandemic,
give it a fancy new name, and then actually CREATE THE PANDEMIC by means
of mass vaccinations using ATTENUATED, or LIVE VIRUSES!! Remember the shocking
words of the AMA's Dr. Simon Louis Katzoff who said: " DOCTORS LIVE
BY DISEASE, SO THE PUBLIC CAN EXPECT THE SUPPLY OF DISEASE TO MEET THE
DEMANDS OF THE MEDICAL PROFESSION."
-
- OTHER DOCUMENTED CASES OF V.I.D.E.O.s (Vaccine Induced
Disease Epidemic Outbreaks.)
-
- Case 1: Following the lead of their colleagues in Kansas
City, the exact same events occurred in Pittsburgh, PA under the direction
of Pittsburgh's "Health Director", Dr. C.J. Voux in the autumn
of 1924. As in Kansas City, a group of public watchdogs brought suit against
Voux and his vaccine-promoters. As in Kansas City, the vaccine promoters
were found guilty. The case documented that over 1,000,000 vaccine shots
were "sold" to the residents of Pennsylvania, even though there
had been ZERO documented cases of smallpox in the region. It was successfully
proven that ONLY AFTER the million shots had been given, that a smallpox
epidemic began.
-
- This vaccine-induced, manmade "epidemic" resulted
in 330 deaths and at least 1,680 cases of severe smallpox that caused permanent,
crippling damage to the survivors. Moreover, it cost the city a total monetary
loss of $3,069,616; although Dr. Voux and his accomplices had collected
more than $10 million in hospital and related care revenues they
were not forced to pay for damages or reparations. As in the Kansas City
trial, a small, insignificant fine was levied, and the case was not widely
publicized.
-
- Case 2: The initial batches of Dr. Jonas Salk's polio
vaccine produced thousands of cases of poliomyelitis in vaccinated individuals.
(One such case was Franklin D. Roosevelt who was stricken weeks after
receiving a vaccine.) This was due to an unsafe amount of LIVE VIRUSES
in the vaccine itself. Dr. Sabin then introduced his "improved"
vaccine with "attenuated" or "weakened' live viruses in
1958, and the following year his vaccine was made to be compulsory (mandatory)
in all school-age children in a number of states. As a result, polio increased
a whopping 300% in these states. For example, Tennessee reported 119 polio
cases in 1958, after "vaccination" this total increased to 386
cases in 1959, Ohio 17 cases in 1958, 52 cases in 1959, Connecticut
45 cases in 1958, 123 cases in 1959, and North Carolina: 78 cases
in 1958 compared to 312 cases in 1959 AFTER forcing compulsory shots in
school children. The modern record is equally damning. The ONLY cases of
recorded polio in the modern era is immediately following vaccinations.
-
- Poliomyelitis, you see, is a water-borne virus and is
caused by drinking contaminated water.
-
- During the early 60's, water-treatment facilities became
standardized across America small amounts of CHLORINATION effectively
wiped out polio viruses. The conquering of polio had NOTHING TO DO with
the vaccine needles and swallowing sugar cubes.
- In fact, as author Ed Haslem documents so well in his
book, "http://doctormarysmonkey.com/" Dr. Mary's Monkey, the
Sabin vaccines were actually contaminated with mutated GREEN MONKEY VIRUSES
(SV-40 viruses to be specific) which has caused untold millions of SOFT-TISSUE
CANCERS and deaths worldwide. (The cancer "industry" has reaped
BILLIONS of dollars from this "contamination" over the years,
of course.) "http://www.youtube.com/watch?v=edikv0zbAlU" Dr.
Maurice Hilleman has actually confessed as being a part of this very activity.
-
- Case 3: Knowingly added to "hepatitis" vaccines,
HIV viruses were inoculated into thousands of homosexual men and intravenous
drug users in America's inner cities resulting in the "AIDS epidemic"
in the 80's. Purposefully placed in SMALLPOX VACCINE SYRINGES, HIV was
also introduced into African nations as a tool of ethnic cleansing and
GENOCIDE. The covert development and weaponization of the HIV/AIDS virus
and its monkey-virus origins, along with the amazing story of how the scientists
involved are tied to President Kennedy's assassination is well documented
in "http://doctormarysmonkey.com/" Dr. Mary's Monkey. The covert
biological experimentation labs responsible for this mayhem are today consolidated
into the NIH, the NAIDS, the National Cancer Institute, and Ft. Detrick,
Maryland. The Centers for Disease Control (CDC) in Atlanta became the centralized
hub of pandemic and epidemic creations and propagation.
-
- Case 4: The 1976 "Swine Flu" Fiasco and Fraud
is perpetrated. A solitary soldier at Ft. Dix collapses and dies following
a reaction to an "experimental" vaccine while completing an intense
physical "forced march" exercise at Ft. Dix. Immediately, the
CDC swings into action, declaring a nationwide SWINE FLU PANDEMIC is pending.
Providentially, of course, the CDC just happens to have 200+MILLION DOSES
of Swine Flu vaccine already stockpiled, prepared with ATTENUATED (live,
yet weakened) viruses and experimental ADJUVANTS.
-
- President Gerald Ford, (with proven ties to Big Pharma
and Nixon's covert viral weapons labs also a key member of the "Warren
Commission's" obfuscation of the JFK murder) rolls up his sleeves
on national TV and dutifully takes the vaccine. 40 million vaccines are
given to naïve American human guinea pigs. A rash of auto-immune disorders
(Guillan-Barre Syndrome GBS, and lupus) as well as a large number of deaths
is immediately attributed to the vaccine, and the mass vaccination campaign
is halted. (What happened to the other 140 million vaccines, one may ask?)
In 1979, the television news magazine 60 Minutes did a documentary investigation
on this travesty-for-money scandal. Against all odds and the threats of
Big Pharma, the OBJECTIVELY FAIR 60 Minutes program aired ONE TIME. There
was no follow-up story, No criminal indictments were ever issued. There
was no MASS- MURDER-FOR-HIRE trial. As a result, America has largely forgotten
the 1976 SWINE FLU SCANDAL! Click here for "http://www.youtube.com/watch?v=5lcJt4jX1Vo"
Part I of the 60 Minutes story; and "http://www.youtube.com/watch?v=r4c9Is1T3z4"
- Part II.
-
- Case 5: During the first Gulf War Operation Desert
Storm, an experimental anthrax vaccine was forcibly given to 140,000 rear-echelon
support troops. This experimental vaccine included an oil-in-water adjuvant
called squalene (aka MF-59 made by NOVARTIS). Despite voluminous studies
showing dangerous toxicity factors conducted on "oil-in-water"
adjuvants at such prestigious research labs as UCLA the U.S. Military
brass consented to the experimental injections. As a result, ALL 140,000
troops developed a condition subsequently named "Gulf War Syndrome".
This sordid tale is explained in a very honest and credible book by "http://www.vaccine-a.com/"
Gary Matsumoto, called, Vaccine-A.
-
- ALL MODERN "PANDEMICS" ARE CAUSED BY VACCINE
NEEDLES
-
- As this author has repeatedly declared during many public
radio interviews, the deadly 1918 Influenza Pandemic was the direct result
of live-virus-contaminated Typhus Fever Vaccines mandatorily given to U.S.
and Allied military personnel during World War I. During that era, viruses
were not yet discovered and diseases were thought to be bacterial only.
These deadly typhus fever vaccines were manufactured by John D. Rockefeller's
research labs and Chinese pharma factories. The vaccine "seed stock"
consisted of viruses harvested from human typhoid fever patients, cross-injected
into swine herds to create increased "seed stock", and then injected
into chicken and turkey eggs for further incubation of the pathogens. The
final, harvested "vaccine material" then was injected into HUNDREDS
OF MILLIONS OF HUMAN VEINS. The result was a massive 'pandemic' that claimed
the lives of as many as 50 million people worldwide.
-
- In 1918, the viral pandemic was an honest mistake
the result of a combination of a very bad vaccine and gross ignorance about
viruses and the diseases they cause. However, the continued denial of these
FACTS, and the subsequent REVERSE ENGINEERING OF THE KILLER VIRUS in Ft.
Detrick labs (1997-2003) is inexcusable and constitutes a veritable crime
against humanity.
-
- Moreover, the ONLY WAY a modern "SWINE FLU PANDEMIC"
can actually materialize is by injection of certain LIVE VIRUSES via vaccine
needles. Make no mistake, the world is NOT experiencing a true pandemic
explosion at this time but it most assuredly WILL when and if the
planned mass influenza vaccinations are completed worldwide.
-
- THE DANGERS INHERENT IN "DUPLEX" VACCINES FROM
DESIGNER VIRUSES
-
- "Modern Medical Practitioners", including some
well-meaning "osteopaths", would have the world believe the MYTH
that vaccines containing attenuated (weakened) live viruses cannot cause
the viral disease conditions they are targeting. This is a most dangerous
misconception for the following SCIENTIFIC reasons.
-
- Traditional "common" vaccines targeting measles,
mumps and rubella for instance, contain small amounts of "attenuated"
live viruses which have been "weakened" but not 100% killed outright.
Research has shown that these weakened "live" viruses create
a very mild form of the disease in the human that has been vaccinated,
which in turn creates a cellular immunity from that pathogen. The science
behind this is correct, and valid for the most part. To keep the targeted
viral pathogen in a perpetually weakened state, specific amounts of formaldehyde
and ether are typically added, and in some formulations, mercury in the
form of thimerasol is added as a preservative to keep the egg albumin cells
from decaying and dying prematurely. The established theory behind all
of this 'vaccination' is the "protect the herd" theory which
originated with Pasteur in the late 19th century. As in all vaccines, a
certain small percentage of the herd will develop severe, 'full blown'
disease states CAUSED by the attenuated viruses in the vaccine itself,
and another percentage will exhibit side effects from the chemicals added
to the vaccine but if the vast majority of the herd is "protected"
from the disease condition the vaccine is approved and stamped "safe
and effective".
-
- Science has also proven that each viral pathogen has
its own unique characteristics that produce its own set of symptoms in
the human hosts. Thus, each viral pathogen has its own unique fingerprints
of replication and reproduction as well. Each virus also has a different
level of effectiveness in its attenuated (weakened) state.
-
- Moreover, some viruses have shown the ability to "drift"
and acquire additional genetic alterations over time. THIS IS ESPECIALLY
TRUE OF THE SO-CALLED "NOVEL" RECOMBINATION VIRUSES that have
been "reverse engineered" in the world's weapons laboratories!
-
- When the RNA of the virus is spliced with other viral
genes, the resulting "Franken-virus" is very unpredictable. Studies
conducted (yet currently unpublished) by Terrence Tumpey, Jeffrey Taubenberger,
and others at the NIH and CDC show that these 'resurrected pandemic viruses'
do not exhibit the NORMAL tendencies of traditional, NATURAL influenza
viruses such as seasonal H3N2 human strains. They are best described as
"Viral Wild Cards".
-
- This is just one problem with the headlong, mad rush
to vaccinate Americans with a series of reverse-engineered lab-created
viruses, attenuated or otherwise, in an UNTESTED, UNTRIED, EXPERIMENTAL
VACCINE that has not been subjected to LONG-TERM CLINICAL TRIALS TO DETERMINE
THE LEVELS OF "DRIFT" or even ATTENUATED TENDENCIES OVER TIME.
-
- To supposedly minimize this "safety" issue,
the CDC is now recommending a DUPLEX vaccination, of all things. A "duplex"
vaccination basically involves a two-shot series. The first shot consists
of a VERY WEAK, HIGHLY ATTENUTATED dose of the live virus.
- This is intended to create an initial immune response
patterning the specific virus injected. Within a couple of weeks of the
1st shot, a BOOSTER SHOT is given. The booster shot has only lightly attenuated,
or even FULL STRENGTH VIRUSES in the injection. This 2nd shot is then intended
to create a full-strength immune system response in the human subject.
-
- This is, at the very least, BAD SCIENCE and borders on
insanity for self-evident and fairly obvious reasons. By their own admissions,
the NIH scientists in their various writings have declared that the level
of potency of these REVERSE ENGINEERED VIRUSES show abnormal, almost RANDOM
tendencies in their attenuated states. Nobody really knows what will happen
over time as the inevitable "genetic drifts" occur. It is a literal
crap shoot. It is highly probable that even the HIGHLY ATTENUATED FRANKEN-VIRUSES
can swiftly regain their FULL POTENCY even in the presence of ether and
formaldehyde. (See Addendum Below) Secondly, the full-strength BOOSTER
shot viruses could just as easily "DRIFT" into something much
more deadly than the "original' recombinant virus that it is targeting.
-
- I submit that the scientists responsible for this "pandemic"
are not stupid. They have to know these facts as well as I do.
-
- Therefore, I can only conclude that this entire affair
is following the Modus Operandi of the medical elite since the 1920 engineered
smallpox epidemics. It is all being ORCHESTRATED first and foremost for
MONEY, and secondly, for social and geographical restructuring of the "human
herd".
-
- Also, it must be understood that this "Novel 2009
Influenza" is not easily nor readily transmissible between humans.
(See published study in the addendum). If this report is accurate, how
then did the "Pandemic" begin, and why the need for mass vaccinations
at all?? Like the "study" shows, the only way the test ferrets
could contract or transmit the 2009 "Novel Swine Flu" was by
and through INOCULATION OF THE DISEASE!! Humanity demands an answer, and
demands it NOW!!!
-
- A.True Ott, Phd, ND
-
-
- Those who cannot remember the past are condemned to repeat
it.
- George Santayana
-
- Those who are ignorant of the past, cannot be expected
to remember it.
- True Ott, PhD, ND
-
-
- ADDENDUM ABSTRACTS FROM SELECTED FRANKEN-VIRUS STUDIES
-
- http://www.ncbi.nlm.nih.gov/pubmed/11226311? ordinalpos=70&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pub
med_DefaultReportPanel.Pubmed_RVDocSum
Feb. 27, 2001
Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment
and characterization of recombinant viruses bearing the 1918 NS genes.
http://www.ncbi.nlm.nih.gov/sites/entrez? Db=pubmed&Cmd=Search&Term=%22Basler%20CF%22%5BAuthor%
5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus<
Basler CF
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Reid%20AH%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Reid AH,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Dybing%20JK%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Dybing JK,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Janczewski%20TA%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Janczewski TA,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Fanning%20TG%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
" Fanning TG,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Zheng%20H%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Zheng H,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Salvatore%20M%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Salvatore M,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Perdue%20ML%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Perdue ML,
http://www.ncbi.nlm.nih.gov/sites/entrezDb=pubmed&Cmd=Search&Term=%
22Swayne%20DE%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Swayne DE,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Garc%C3%ADaSastre%20A%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
García-Sastre A,
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%
22Palese%20P%22%5BAuthor% 5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Palese P,
http://www.ncbi.nlm.nih.gov/sites/entrez? Db=pubmed&Cmd=Search&Term=%22Taubenberger%20JK%22%5BAuthor%
5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_Discove
ryPanel.Pubmed_RVAbstractPlus
Tumpey TM.
Influenza Division, National Center for Immunization and Respiratory Diseases,
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. Recent
reports of mild to severe influenza-like illness in humans caused by a
novel swine-origin 2009 A(H1N1) influenza virus underscore the need to
better understand the pathogenesis and transmission of these viruses in
mammals. In this study, selected 2009 A(H1N1) influenza isolates were assessed
for their ability to cause disease in mice and ferrets and compared with
a contemporary seasonal H1N1 virus for their ability to transmit to naïve
ferrets through respiratory droplets. In contrast to seasonal influenza
H1N1 virus, 2009 A(H1N1) influenza viruses caused increased morbidity,
replicated to higher titers in lung tissue, and were recovered from the
intestinal tract of intranasally inoculated ferrets. The 2009 A(H1N1) influenza
viruses exhibited less efficient respiratory droplet transmission in ferrets
in comparison with the highly transmissible phenotype of a seasonal H1N1
virus. Transmission of the 2009 A(H1N1) influenza viruses was further corroborated
by characterizing the binding specificity of the viral hemagglutinin to
the sialylated glycan receptors (in the human host) by use of dose-dependent
direct receptor-binding and human lung tissue-binding assays.
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