- The CDC is recommending the swine flu vaccine to everyone.
- In its promotion of the swine flu vaccines, the CDC is
making no distinction between vaccines that will contain live attenuated
influenza virus (LAIV) and those containing inactivated (dead) virus and
squalene, an adjuvant.
- The novel H1N1 vaccine is expected to be available in
the fall--a specific date has not been released but early October seems
likely--and patients with compromised immune systems will be among the
first in line recommended to be vaccinated.
- Following a meeting in late July, CDC issued a press
release recommending the vaccination efforts focus on five key populations
- : ...
- * pregnant women,
- * people who live with or care for children younger than
6 months of age,
- * health care and emergency medical services
- * persons between the ages of 6 months and 24 years of
- * people from ages 25 through 64 who are at higher risk
for novel H1N1 because of chronic health disorders or compromised immune
- The groups listed total approximately 159 million people
in the US.
- The committee does not expect that there will be a shortage
of the vaccine but warns that availability and demand can be unpredictable.
If there is a shortage, first in line will include: pregnant women, people
who live with children less than 6 months of age, health care and emergency
personnel with direct patient contact, children 6 months through 4 years
of age, and children 5 through 18 years of age who have chronic medical
- But in 2003, the CDC said:
- "The following populations should not be vaccinated
with LAIV":persons aged 50 years;
- Unpublished data from a study including subjects aged
1--17 years indicated an increase in asthma or reactive airways disease
in the subset aged 12--59 months. Because of this, LAIV is not approved
for use among children aged 60 months.
- persons with asthma, reactive airways disease or other
chronic disorders of the pulmonary or cardiovascular systems; persons with
other underlying medical conditions, including such metabolic diseases
as diabetes, renal dysfunction, and hemoglobinopathies; or persons with
known or suspected immunodeficiency diseases or who are receiving immunosuppressive
therapies; children or adolescents receiving aspirin or other salicylates
(because of the association of Reye syndrome with wild-type influenza infection);
persons with a history of Guillain-Barré syndrome; pregnant women;
or persons with a history of hypersensitivity, including anaphylaxis, to
any of the components of LAIV or to eggs.
- It also said:
- "LAIV is intended for intranasal administration
only and should not be administered by the intramuscular,
intradermal, or intravenous route."
- Some of the swine flu vaccines will contain live attenuated
virus yet the CDC is recommending the vaccines be given to all ages and
all populations with no differentiation based on those who might react
poorly to the vaccine. Its own 2003 list of those who should not
receive LAIV has in 2009 become its list of those who should be first in
line to receive it.
- In addition, despite its admonition in 2003 that the
vaccine not be given intramuscularly to anyone, in 2009 the vaccines, including
those with LAIV, will be given intramuscularly to everyone.
- Why are there suddenly no contraindications at all for
- Is this not in complete contradistinction to what has
always been true in the past when prescribing vaccines and all other medical
- Why are those who were contraindicated in 2003 suddenly
first in line for vaccines with LAIV in 2009?
- Why is the LAIV vaccine being given intramuscularly despite
the fact that the CDC specifically warned against doing so in 2003?
- Are people with hypersensitivity to eggs, including anaphylaxis,
simply supposed to take the vaccines and die?
- Anaphylaxis is an acute systemic (multi-system)
and severe type I hypersensitivity allergic reaction in
humans and other mammals. The term comes from the Greek words ; ana (against)
and ; phylaxis (protection). Minute amounts of allergens
may cause a life-threatening anaphylactic reaction. Anaphylaxis may occur
after ingestion, skin contact, injection of an allergen or, in some cases,
- Anaphylactic shock, the most severe type of anaphylaxis,
occurs when an allergic response triggers a quick release of large quantities
of immunological mediators (histamines, prostaglandins and leukotrienes)
from mast cells, leading to systemic vasodilation (associated
with a sudden drop in blood pressure) and edema of bronchial
mucosa (resulting in bronchoconstriction and difficulty
breathing). Anaphylactic shock can lead to death in a matter of minutes
if left untreated.