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H5N1 Bird Flu Now
Infecting Pigs In Indonesia

From Patricia Doyle, PhD
dr_p_doyle@hotmail.com
4-13-5
 
[1]
From: Irene Lai
Date: Tue, 12 Apr 2005
Source: Kompas, 9 Apr 2005 [translated from Indonesian, edited]
 
Indonesia: Avian Influenza Virus Identified in Pigs
 
Ca Nidom, a molecular biology researcher from [the Centre for] Tropical Disease Control, Airlangga University, Surabaya, East Java, has reportedly identified avian influenza virus in throat swabs and sera of pigs by RT-PCR. [District location not mentioned].
 
Inactivated RNA isolates have been sent to the Tokyo University, where 8 fragments (HA, NA, PA, PB1, PB2, M, NP, NS) were sequenced. Results showed that the virus was [structurally?] similar to the avian influenza virus from poultry, and is characterised by high pathogenicity (based on the study regarding the cleavage site).
 
Dr. Irene Lai
International SOS
 
******
[2]
Date: Tue, 12 Apr 2005
From: Irene Lai
Source: Kompas, 5 Apr 2005 [5 first paragraphs translated from
Indonesian, edited]
http://www.kompas.com/kompas%2Dcetak/0504/12/ekonomi/1676599.htm
 
Indonesia: Agriculture Department To Investigate Avian Influenza Virus In Pigs
 
The Department of Agriculture will study the discovery of avian influenza virus from infected pigs. The agriculture department will carry out sampling from several pig farms. More research is needed, especially regarding the background and route through which the infection of pigs with avian flu virus took place.
 
The Minister of Agriculture, Anton Apriyantono, said to the journalist on Mon, 11 Apr 2005 in Jakarta, that his staff has already ordered the General Director of Farming Production to investigate that finding. "We need confirmation because the news is not clear yet. First, it is not clear where the pigs are originally from, what is their current location and which type of pigs have been involved". The General Director of Farming Production will assist the veterinary investigators in studying samples from pigs. "We are already working on it", said Anton
 
As broadcast on Saturday, the molecular biology researcher in Airlangga University, CA Nidom, discovered the avian influenza virus in pigs. The finding was based on identification of [DNA/RNA?] and might be interpreted as indicative for the presence of new avian influenza cases in Indonesia. "We are responding to that report by taking samples from pigs in Indonesia. Is it correct that pigs have been infected? For me this is still the question", he said.
 
Dr. Irene Lai International SOS
 
[ProMED-mail is grateful to Dr Lai for sending us the above translated reports. - Mod.AS]
 
These reports are somewhat contradictory. On the one hand it is suggested that the complete genome of an avian influenza virus isolated from a pig in Indonesia has been sequenced from RT-PCR fragments, whereas on the other hand the presence of avian influenza virus infection in pigs in Indonesia has still to be confirmed by isolation of infectious virus. The serotype of the virus does not appear to have been established, so it cannot be assumed at this stage that the virus is the H5N1 East Asian epidemic strain.
 
However, although the situation is somewhat confused, these reports cannot be dismissed lightly, because the presence of H5N1 virus in pigs might increase the risk of adaptation of the epidemic avian influenza virus to growth and transmission in mammals -- although it should be emphasized that the role of pigs as mixing vessels in the generation of pandemic influenza viruses is no more than a hypothesis. Further information is awaited with some apprehension. -Mod.CP
 
 
Patricia A. Doyle, PhD
Please visit my "Emerging Diseases" message board at: http://www.clickitnews.com/ubbthreads/postlist.php?
Cat=&Board=emergingdiseases
Zhan le Devlesa tai sastimasa
Go with God and in Good Health


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