- ANAHEIM, Calif. (AP) -- Getting
enough vitamin D may be a matter of life or death ñ a provocative
new study suggests that it plays an important role in surviving lung cancer.
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- People can obtain the nutrient from their food, vitamin
pills or being out in the sunshine. Researchers found that the lung-cancer
patients with high intake who had surgery during the summer were more than
twice as likely to be alive five years later than those with low levels
who had operations in winter.
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- It is one of several recent studies to show the benefits
of the "sunshine vitamin" against cancer.
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- "There are a lot of data emerging from various areas
suggesting it is important," said Dr. Edward Giovannucci, professor
of nutrition and epidemiology at the Harvard School of Public Health.
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- He helped conduct what is believed to be the first human
study to look at vitamin D and lung cancer survival. The results were reported
Tuesday at an American Association for Cancer Research conference in Anaheim.
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- "This is a very interesting study. It's a new trend
ñ looking at dietary factors as they relate to survival," not
just the risk of getting a certain cancer, said Dr. Michael Thun, chief
epidemiologist at the American Cancer Society, who had no role in the research.
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- Vitamin D is made by the skin from sunlight. Getting
enough from diet alone is tough ñ fish and fortified milk are the
main sources. Supplements are controversial, because too much D can cause
medical problems, but many scientists think the recommended daily level
of 400 international units is too low.
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- The nutrient has many features that could explain its
possible benefit against cancer, such as stifling cell growth. Doctors
had seen evidence suggesting that it prevents some cancers, and they wanted
to know if it also affected survival.
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- Led by Harvard University's Dr. David Christiani, they
studied 456 consecutive patients with early-stage lung cancer at Massachusetts
General Hospital, Brigham and Women's Hospital and Dana-Farber Cancer Institute.
Patients were interviewed about diet, supplements and timing of their cancer
surgery, which was thought to be another indicator of their vitamin D levels.
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- Those who had high vitamin D levels and summer operations
fared the best: five-year survival was 72 per cent versus 29 per cent for
those who had the lowest levels of the nutrient and winter surgery.
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- This does not mean that people should delay or try to
time operations, but taking vitamin D supplements about the time of surgery
might be a good idea, said Wei Zhou, a Harvard researcher who presented
the study results.
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- If verified by larger experiments, "this would be
considered an important gain," said Dr. Thun of the cancer society.
"A benefit of this size is important for this highly lethal disease."
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- Lung cancer is the world's top cancer killer. About 172,500
new cases and 163,510 deaths are expected this year in the United States,
and more than 1.3 million cases and nearly 1.2 million deaths worldwide.
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