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Did Vaccinations Give Fatal
Marburg To Angolan Kids?
From Patricia Doyle, PhD
dr_p_doyle@hotmail.com
4-2-5

Excerpt:
 
Angola: Further Comment on the Unusual Age Distribution of Cases
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To extend on Dan Bausch's hypothesis of an iatrogenic explanation for the unusual age distribution in the current Marburg hemorrhagic fever outbreak [see ProMED-mail post: "Marburg hemorrhagic fever - Angola (11): age distribution 20050331.0935]: In addition to in-hospital transmission, the teams in the field may wish to investigate 2 other possibilities for iatrogenic transmission: (1) invasive outreach activities like vaccination and (2) traditional medical practices like scarification, provided they target children.
 
MARBURG HEMORRHAGIC FEVER - ANGOLA (12)
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A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
 
[1]
Date: Fri 1 Apr 2005
Source: World Health Organisation (WHO), CSR, Disease Outbreak News, Fri 1
Apr 2005 [edited]
http://www.who.int/csr/don/2005_04_01/en/
 
Angola: Marburg Virus Disease - WHO Update 5
--------------------------------------------
As of Thu 31 Mar 2005, 140 cases of Marburg virus disease have been reported in Angola. Of these, 132 have been fatal. Cases continue to be concentrated in Uige.
 
Mobile surveillance teams in Uige continue to follow up on rumours and conduct active searches for additional cases. Contact tracing has also been intensified. These activities are now supported by a mobile laboratory in Uige, which has greatly expedited diagnostic testing.
 
WHO is working with the Ministry of Health in the Democratic Republic of Congo to train local staff in the border area near Angola in case detection and management.
 
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[2]
Angola: Marburg Disease Outbreak Is The Deadliest Ever
4-1-5
 
(Reuters) --The outbreak of Marburg hemorrhagic fever in Angola has claimed 127 [now 132 -- see above] lives, the highest number of fatalities ever recorded from the rare deadly disease, the World Health Organization (WHO) said on Fri 1 Apr 2005.
 
In a statement, the United Nations agency also said it was sending more experts to Angola at the weekend, including a medical anthropologist to teach about preventing the spread of the virus during traditional burial practices. The WHO has deployed 20 experts to help combat the viral hemorrhagic fever, characterized by headaches, nausea, vomiting and bloody diarrhea. It is spread through close contact with bodily fluids including saliva and perspiration.
 
Since October there have been 132 cases of Marburg hemorrhagic fever, causing 127 deaths, mainly in Angola's northern Uige province. A 15-year-old boy who died on 20 Mar 2005 is the only known victim in the capital Luanda, WHO spokeswoman Fadela Chaib told a briefing. "This is the largest number of fatalities ever recorded during an outbreak of this rare but extremely severe disease," the WHO said. The previous record was 123 deaths among 149 cases during an epidemic from late 1998-2000 in the Democratic Republic of Congo. Most victims were gold miners.
 
The WHO is also sending a further 500 kilos (1100 lbs) of protective equipment to protect hospital workers and other front-line staff in Angola. "Marburg can be controlled if people are put in isolation and their contacts are traced," Chaib said.
 
Health officials were also tracing travelers rumored to have been exposed to the disease in Angola, including 9 people now isolated in hospital in Italy, according to the WHO spokeswoman. Tests on two travelers who went from Angola to Portugal showed they did not have the disease, she added.
 
-- ProMED-mail
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*****
[3]
Date: Fri 1 Apr 2005
 
Suspected Marburg Fever Cases In Democratic Republic Of Congo And Italy
 
News24.com (South Africa)
4-1-5
 
Italian hospital staff have put 9 patients in isolation after they had been suspected of having contact with Marburg virus, the World Health Organisation (WHO) stated on Fri 1 Apr 2005. A WHO spokesperson, Fadela Chaib, said 2 other suspected cases had been reported in the Democratic Republic of Congo (DRC), across the border from the north Angola area where the outbreak began and has claimed 127 lives out of 132 cases.
 
"9 people who were in contact with an ill person have been isolated in an Italian hospital," Chaib said, without giving details of in which town or the nationality the suspected fever patients. Last week, an Italian paediatrician died of haemorrhagic fever in Angola, according to Medici con Africa, the relief organisation for which she worked. The WHO was unable to say whether the 9 patients in Italy had been in touch with this woman.
 
The death toll of 127 out of the 132 people who contracted Marburg fever in an outbreak that started 6 months ago in the north of Angola came from data released by the WHO on Fri 1 Apr 2005. Angolan authorities on Thu 31 Mar 2005 officially put the toll from the virus at 126, the world's highest, as Canada sent a mobile laboratory to help investigate suspected cases. The epicentre of the outbreak is Angola's northern Uige province.
 
http://www.news24.com/News24/World/News/
0,,2-10-1462_1684040,00.html
--
ProMED-mail
promed@promedmail.org
 
******
[4]
Date: Fri 1 Apr 2005
From: ProMED-mail <promed@promedmail.org>
Source: IOL online, SADC, Agence France Presse report, Fri 1 Apr 2005 [edited]
 
Angola: Marburg Virus Reaches a Fourth Province - Kwanza Norte
 
(AFP) -- Marburg virus has reached a 4th province in Angola, bringing the nationwide toll from the Ebola-like disease to 130, Angola's Health Ministry and the World Health Organisation said on Fri 1 Apr 2005. "By Thu 31 Mar 2005 a total of 137 cases, 130 of them fatal, have been recorded," the joint commission monitoring the epidemic said in a daily briefing document, adding that the virus had spread to Kwanza Norte province east of the capital. The official death toll from the disease had stood at 126 on Thursday, since the worst global outbreak of the virus started 6 months ago.
 
3 more deaths have been recorded in the province surrounding the capital Luanda, in Kwanza Norte province and in Uige -- the northern province which has been worst hit by the virus. No details were available about a 4th death. The case in Kwanza Norte was recorded in the town of Camabatela, which lies 85km south of Uige and 300km east of the coastal capital. The health ministry called on the population to help control the epidemic by alerting the authorities of any deaths in the home. It also urged people not to touch the bodies of the deceased and to keep the authorities informed about individuals who may have been contact with the sick.
 
A severe form of haemorrhagic fever akin to Ebola, Marburg virus was first identified in 1967. It spreads on contact with the fluids the body produces in reaction to it, such as blood, urine, excrement, vomit and saliva. The Marburg outbreak has claimed a record number of lives, overtaking the earlier peak in the Democratic Republic of Congo, Angola's neighbour.
 
The WHO is to send medical reinforcements to Angola over the weekend to help cope with the crisis. The commission tackling the Angolan epidemic comprises WHO specialists, as well as experts from Medecins sans Frontieres, and from the US-based Centers for Disease Control.
 
http://www.iol.co.za/index.php?set_id=1&click_i
d=84&art_id=qw1112362021616B252
 
--
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promed@promedmail.org
 
******
[5]
Date: Fri 1 Apr 2005
From: Matthias Borchert
Matthias.Borchert@lshtm.ac.uk
 
Angola: Further Comment on the Unusual Age Distribution of Cases
 
To extend on Dan Bausch's hypothesis of an iatrogenic explanation for the unusual age distribution in the current Marburg hemorrhagic fever outbreak [see ProMED-mail post: "Marburg hemorrhagic fever - Angola (11): age distribution 20050331.0935]: In addition to in-hospital transmission, the teams in the field may wish to investigate 2 other possibilities for iatrogenic transmission: (1) invasive outreach activities like vaccination and (2) traditional medical practices like scarification, provided they target children.
_____
 
Matthias Borchert MD MSc
Clinical Lecturer
London School of Hygiene & Tropical Medicine
ITD/IDEU
Keppel Street, room 257
London WC1E 7HT
matthias.borchert@lshtm.ac.uk
 
(In summary, the death toll in the current Marburg hemorrhagic fever outbreak in Angola now exceeds that of the previous highest outbreak total recorded in the Democratic Republic of Congo in 1998-2000. As of Thu 31 Mar 2005, there have been 9 fewer cases but 9 more deaths in Angola. 2 suspected cases have been reported from the adjacent Democratic Republic of Congo and 9 suspected cases of unknown provenance hospitalised in Italy. - Mod.CP)...mpp/cp/pg/mpp
 
Patricia A. Doyle, PhD
Please visit my "Emerging Diseases" message board at: http://www.clickitnews.com/ubbthreads/postlist.php?
Cat=&Board=emergingdiseases
Zhan le Devlesa tai sastimasa
Go with God and in Good Health


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