- This monologue is presented to orient persons, using
plain language, to the problems associated with fluorine and fluoride chemicals.
-
- If I were to name one element or one chemical compound
that would represent the "Bane of Mans existence on Earth" it
would be fluorine or fluoride. Fluorine has caused huge problems for man
since the beginning of time due to volcanic effects on Earth. Fluorine
or Hydrogen Fluoride released from volcanic events or even meteor terminal
events is the principle effect for extinction events on this planet.
-
- Fluoride in the body rises constantly with age and there
is even one excellent book named for this effect: "Fluoride The Aging
Factor" by Dr. John Yiamouyiannis [ISBN 0-913571-03-2]. Fluoride increases
in the bones with age and all the effects of aging leading to immune system
dysfunction and death track the retention of fluoride in the human body.
Yianouyiannis and others have picked up on this effect. See excerpts of
his book: Click Here and Here.
-
- The industrial age has brought on a huge rise in the
levels of fluoride in the air, water, and food supplies. Persons like German
doctor Waldbott were some of the first to begin to point out the problems
of fluoride. One of his books even presents the issue as the Dilemma: "Fluoride
The Great Dilemma" by George Waldbott, MD [ISBN 0-87291-097-0] with
foreword by Alton Ochsner, MD. Waldbott has this book foreword'd by one
of the lead persons on the kill Castro with Cancer methods using SV-40
effects with a trigger of radiation or fluoride. See book excerpts: Waldbott
Book.
-
- More recent books speak to the huge cover up of industry
and the US Govt. on the issues of fluoride connected to the nuclear bomb
and strategic metals processing, see: "The Fluoride Deception"
by Christopher Bryson [ISBN 1-58322-526-9]. Book Review. The health damages
due to fluoride releases of these operations were so destructive that the
Govt. with industry partners [DuPont, ALCOA, Rockefellers, Kettering Labs
of Cincinatti, Oh.] decided to conceal the effects from the public. Kettering
Labs is located where the occupation illness center in the US is located
and Kettering is funded by the polluters and most all their files on fluoride
research are kept locked away from the public. This has lead to extreme
levels of abuse toward citizens and their health in the name of attempting
to defeat communism. See: Kettering History.
-
- Fluoride has been used as a pesticide for centuries and
when looks for the method of which it kills bugs one quickly discovers
the mechanism involves the upsetting of trace metal metabolism within cells.
In insecticide uses, higher concentrations are applied, but when these
same poisons enter the human food chain these same effects happen, only
more slowly. Every human on the face of planet Earth is affected by this
fluoride effect, some more that others depending on geographic, food consumption,
industry, and water pollution. Fluoride is cumulative from even the subtlest
levels taken in by human consumption.
-
- The key to understanding the most damaging effect of
fluoride is to know about these trace metal upsets that control enzyme
repairs and other processes within cells. Upsets in these trace metals
occur due to the fact that fluorine is the most electronegative element
and when present within the body will cease onto trace metals spontaneously.
This effect keeps these trace metals from being able to do their essential
uses with the body and cells. This effect leads to rise in cell damages,
higher levels of oxidation like damage to DNA, rises in the cytokine levels,
loss of immune system tolerance in detection and elimination of varied
pathogens, etc.
-
- The problems associated with fluoride don't stop with
the metals-complex issues, as fluoride damage thyroid hormone due to iodine
like valence effects, it damages the pineal gland and the melatonin / serotonin
hormones, it contributes to arterial plaque, it upsets many of the immune
cells like macrophage energy, it associates to heart attacks, kidney damage,
and etc. If there were one element that was associated with the God of
the Underground, Death, and Hell; it would be fluorine.
-
- Fluoride effects are directly related to loss of IQ in
children and the dumbing down of the population that makes them easier
to lead. Fluoride effects linked to aluminum are linked to the passage
of aluminum across the blood-brain-barrier that is linked with Alzheimer's
effects. Fluorides complex with aluminum to form G-protein like substances
that are able to permanently upset cell bonding sites. Fluorides increase
the retention of toxic metals in the body and lower the retention of beneficial
trace metals, and this is a death keel to essential enzyme processes.
-
- Fluorine was a large factor in the health problems in
London due to the "London Fogs" that stemmed from the burning
of high fluoride "Sea Coal." These emissions produced fogs so
thick they were called "Pea Soup" and persons had to lead carriages
around the streets in broad daylight with lanterns. It is this same area
that spawned the problems connected to Jack the Ripper, who appeared to
be looking at the health effects of prostitutes connected to these toxic
effects. A good book that goes into some of this is: "When Smoke Runs
Like Water" by Dr. Devra Davis [ISBN 0-465-01521-1]. See excerpts:
Here.
-
- Fluorine began being exposed industrially in the 1930s
in the Meuse Valley in Belgium from the emissions of aluminum processes,
where it is used as a flux and melting point modifier for aluminum smelting.
In the US in 1948, fluoride became a huge issue for the Donora, Pa. air
inversion that trapped coal smoke and fluoride vapors from the flux operations
of the steel mills there.
-
- In the 40s era Manhattan Project it was a huge problem
connected to national security and huge accidents near Buffalo, NY were
concealed and problems from DuPont's Peach Bottoms emissions were the start
of huge Govt. sponsored cover ups on the damaging effects of fluorine processes.
Fluorine was the only element that led to the lowest temperature gaseous
form of uranium compounds.
-
- One can see there formed a Govt. and industry sponsored
cover up of the dangers of fluoride that matured into something to make
it associated with good for children's teeth. The truth of this deceptive
process is that it put a deadly poison within the reach of nearly every
child in America. The deadly truth is there is enough fluoride in one tube
of the sweet and flavored toothpaste to kill an adult. Short of doses that
kill the fluorides toxic effect robs children of their IQ, robs them of
essential trace metals needed to immune health, and leaves them with a
lifelong predisposition toward cancers, immune illnesses, and HIV.
-
- When one knows and recognizes the issues of fluorine
intake affecting the immune system, then other factors come into view.
For example, rodents have long been associated with spreading the Black
Plague bacteria in Europe. Most of these outbreaks have occurred correlated
with major volcanic events. Rodents like to chew on bones to sharpen their
teeth and this also puts high levels of fluorine into their diets. These
levels tend to rise after volcanic events and this is associated to the
immunity being damaged to the extent that the black plague bacteria are
not controlled.
-
- Since rodents have naturally been exposed to much higher
levels of fluoride in their food chain due to the bone consumption, this
effect has also upset the data derived from their use in medical research.
Reference 1 below speaks to the finding of rodents by Wake Forest University
with drastically different immune responses to cancer that all previous
line of mice used in cancer research. The long isolation of mouse lines
in captivity and their being fed low fluoride diets have lead to some of
them recovering their immune functions. This basically means that all the
data collected with mice has been flawed by the generational damage done
by fluoride.
-
- Bone meal fluoride is a huge undisclosed problem. It
shows up in cattle fed bone meal leading to the issues of Mad-Cow or BSE.
It shows up in gardeners who use bone meal on food they consume who then
come down with similar illnesses. And it has shown up in children fed "pablum,"
which was made from bone meal.
-
- Natural fluoride effects even upset the reproduction
of salmon fish, which must migrate into fresh water with less than the
1ppm fluoride in sea water. Various fish hatcheries have been harmed by
fluoride levels of only 0.5 ppm in varied industrial cases.
-
- Fluoride taken into the stomach is converted by the stomach
acid to hydrofluoric acid, which is highly absorbed into the body and highly
retained. It is a cumulative effect. The effect is most pronounced in rodents
that consume bones that highly concentrate fluorine from the environment.
The effect highly drives cancer resistance. This effect entered the studies
on cancer as a weapon against Castro using SV-40 mutations.
-
- DuPont's mess made from fluorine not only made an ecological
disaster from the Manhattan Project, it went on to wreck the world and
even individual children's young lives. DuPont made the lead for leaded
gasoline. DuPont made the fluorine to make the UF-6 used to make the bomb
uranium and they made the Teflon used to seal the processes and the Freon
used to remove the heat of compression from the gas diffusion process.
The Freon would go on to wreck the global environment due to the Fluorine
being so close in mass to air that it lingers and builds in the upper atmosphere.
Here it absorbs high levels of IR radiation and contributes to global warming
and also sequesters hydrogen that adds to the UV-b levels from ionization
effects.
-
- The DuPont mess does not end there as the stain resistant
compounds like "Scotchguard" is tied to Infant Deaths. Infants
tend to burp up stomach contents and this gets onto Scotchguard surfaces
of baby mattresses. Here the acid liberates the fluoride used in the stain
resistant coating and makes HF, which can cause SIDS. Scotchguard has recently
been discontinued due to these effects, in the same way that Freon has
been discontinued. DuPont's Teflon was even seen to break down in cooking
applications and poison and kill household birds.
-
- The Manhattan Project is riddled with fluorine problems.
The very first deaths connected with the project came from liquid diffusion
experiments hitting some water causing a huge explosion and HF release
that killed several people. The problems never ceased, as in Oak Ridge
they killed a worker named Jack Owens who sat on some "Green Salt"
at the Y-12 plant that was wet with HF and he died of a heart attack a
few days later. HF has a sudden death effect due to skin absorption effects
on the heart. Persons like Paducah's Joe Harding cleaned out gas diffusion
equipment and received HF exposures by crawling around and getting HF into
his tendons around knees, elbows, etc. The fluoride hardened his ligaments
and these would flake off and look like fingernails coming through his
skin. He eventually died of stomach cancer.
-
- Fluoride even has some more sinister uses, as it was
used in Russia and in Germany to pacify prisoners. The infamous "Red
Trains" of Russia took undesirables to work camps in Siberia. Here
the Jewish operators of these camps administered the fluoride to change
resistant attitudes. Ironically, Jewish Communist in Russia banned religions
due to some of the problems of state within a state effect that religion
caused that challenged the power of Governments. Many of these religious
dissidents landed in these Jewish operated Siberian prisons and were given
the same methods of treatment that Moses dealt to the Egyptians using the
alchemical methods of fluoride.
-
- The people of Russia and Europe have rejected the use
of fluoridation because they know of its more sinister properties in taking
control of societies. The Russian Jews that banned religions also likely
saw through the real alchemical meanings from the veiled messages and parables
presented in the Torah. Meanwhile, these communists stood by and watched
the problems that wrecked Europe for so long be pilloried against the US
and the UK. The toxic methods of fluoride have so lamed the minds of citizens
of these countries that they don't even notice the greater plan to take
over the country from within, as forecast by Russia's Khrushchev. Fluoride
has some very sinister purposes once the Old World religion meanings are
unveiled.
-
- Fluorides released from industry causes problems and
more sinister uses of fluorides to control people also cause problems.
Natural effects are not exempted as even natural effects of fluoride levels
are tied to the transmission of HIV and the resultant pandemic. The East
African Rift Zone in Africa has the highest levels of HIV cases, and these
areas also have the highest levels of fluoride in their food and water.
Ref 2 below speaks to the issue of manganese being able to stop HIV reverse
transcription replication and transmission in its tracks. This is one of
the fluorine-metal complex effects that make for the problems of the HIV
pandemic. The use of fluoride here is population control, and the Govt.
does know the real issues behind HIV. It fits the Rockefeller depopulation
plans.
-
- In the human body the HIV virus tends to remain latent
in the immune system cells of the abdomen, which is where the food and
water intake would tend to affect the immune system the most. Other factors
like gay male's seamen also add to the concentration effects of fluorides
because it tends to concentrate the fluoride toxics. Add to this that drugs
like cocaine also affect the immune system and make HIV more infectious.
This is how the gay population was so heavily affected by HIV.
-
- The real issues of natural effects of fluoride and ever
more sinister uses for it appear far back in history. Fluoride issues go
back to the times of the origin of Alchemy in Egypt and the parable presentations
in the Biblical narratives. The Egyptians were into religious rights used
at mining temples to gather and purify gold. This was the source of the
black chemistry called Alchemy. The Egyptians appear to be some of the
first to observe that gold could be used as a medicine effect.
-
- They did not know why at the time, only that it aided
health. Today, we can see that gold added to the body tends to complex
with fluorine and render it less harmful. This later went into how the
Jews of Exodus survived the toxic effects of the Mt. Sinai volcano next
to Midian. They added gold to their cooking methods as told by the golden
calf story. Even today, the Chinese believe in adding gold flakes to their
food and even cooking with a gold coin to achieve these same effect. We
can see similar effects on the immune system and the susceptibility to
flu be adding increased zinc to ones diet.
-
- Moses was exposed to this mining temple Alchemy science
linked to gold for the Egyptian royal courts. When Moses came for his people
he used poison methods that were presented in alchemical imagery terms
linked to symbols of the snake and the staff as power. Moses took his people
to the Mt. Sinai volcano and here they did the mining techniques to extract
gold from its deposits. They learned to survive the HF emissions by using
the gold techniques. This is the heart of the science of colloid gold and
silver, because these nano-fine particles gain entrance into the body and
cells and can render the fluoride effect harmless by complexing with the
fluorine atoms.
-
- Even when get up to the times of Jesus we see the Egyptian
Alchemy being involved linked to "Star Metals." The only thing
the Egyptians valued more than gold was the "Star Metal," which
was basically just low carbon iron from meteorites. It was the steel of
the times, and highly valued. It was this substance that the Three Wise
Men story of Jesus' birth relates. The Jews wanted a new savior and the
Wise Men liked the concept and imparted with them the inner secrets of
the Alchemy.
-
- Mary, Joseph, and thus Jesus learned the inner meanings
of the story of Genesis and the methods of Moses and his volcano Alchemy
from their contact with the alchemical wise men. They could then see through
issues of the Jewish Torah in ways that had not been presented by Holy
Rabbis of the times. Due to this inspirational epiphany of Mary and Joseph,
Jesus became the reformer for the Jews over these inner secrets of the
Torah (Torah is the first five chapters of Christian's Bible). Even when
we go back to Noah, we find the volcanic effects link to 40 days and nights
of rain and the need to sequester food and shelter animals from the poisons
of these events.
-
- We can see these similar effects on animals today from
volcanic events in Iceland, where the HF is cooled and deposited on the
snows that melt and flow into rivers. The cattle and other animals hundreds
of miles away from these events are often killed by drinking the HF contaminated
water from the rivers. Similar effects are seen around aluminum plants
where cows eat contaminated grass and either die or suffer extreme degenerative
health effects.
-
- Even the parable on Sodom and Gomorrah is one about the
Dead Sea regions rift zone, which due to pressure and volcanic issues released
all matter of fluorides into the ground water and wells of the region.
What followed was toxic effects on the population there and the story that
God or Nature destroyed them as it sank beneath the Dead Sea. This story
is little different than the current problems in Ethiopia, where fluoride
levels are extremely high in the water supplies and the rift effects are
going to make in inland ocean of a large part of the country due to subsidence
of the land.
-
- We can even see the aphrodisiac effects of fluorides
from the parables on Sodom and Gomorrah, and the very same effects happen
to workers of the Govt.'s nuclear plants in Oak Ridge. These sex drive
effects were so bad that all the office and lab windows and door glass
had to be removed and replaced with clear glass to limit the private areas
for sexual activities. Oak Ridge and other sites that experienced the toxic
effects of fluorides got a unique visit back in time to the problems seen
in the biblical narratives. It is how places like Oak Ridge unlocked the
deeper issues of God and Nature from the Bible's stories.
-
- The secrets of religion are directly related to the alchemical
science that evolved around the effects of fluorine from the Old World
and the stories of the Old Testament. Jesus and the New Testament set forth
to challenge the Torah and the Solomon's Temple Jews or Pharisee that misinterpreted
these alchemical images stories. Jesus held the greater sense on what was
and was not God. The Old Testament is really the anti-Christ and the New
is the Christ, and this is where the ultimate story of understanding the
most electronegative element on the planet leads.
-
- Those that truly understand the messages of Jesus would
have to note that his message is about "Health Care" by prevention
and not the "Illness Care" methods of today that have gone wild
due to the suppression of toxic effects on the world population. Jesus
was an Environmentalist of his times and he spoke against the deceptive
war methods of Moses' God using fluoride alchemical chemical warfare. This
is the message shown in imagery by Mary standing on the Snake with an apple
in its mouth to control the levels of poisons getting into the human food
chain. It is the story of putting only good things into the body and treating
it as a temple.
-
- The science of fluorine is literally so pontifical that
it is the divine gatekeeper between what are the concepts of Heaven and
Hell for Humans on this planet. This is how powerful the study of the full
issues of fluorine relates. Fluorine gets into the inner circle of the
secrets of religion, and the flaws in the interpretations of religion.
This is how fluorine comes to play such an instrumental role in the Revelations
message of Jesus from the Biblical narratives.
-
- Fluorine effects are directly linked to the great health
plagues of cancer and HIV that we see today, as prophesied by Jesus in
the Revelation narratives. The major weather effects are directly connected
to the global warming effects being generated by fluorine building in the
upper atmosphere. The full understanding of the effects of fluorine lead
to the life-spans of 1,000 years presented in the Biblical Narratives Genesis.
This being the best interpretation for "Eternal Life" and the
saving messages from Jesus.
-
- The Manhattan Project has played a pivotal role in the
keeping of these huge secrets that have falsely empowered and mislead so
many. It is linked to the messages of the End-Times, when false prophets
have surrounded us. The Manhattan Project likes to falsely play up that
radiation is the cause of the many health problems, but this is only an
intentional misleading story salted into the public's mind. The Manhattan
Project and religion have long been linked in a mutual act of preservation
of huge lies that are harmful to all citizens of this planet.
-
- If the church gives up its inner sanctum secrets liked
to these effects or the Manhattan Project scientists tell the real relationships,
then both sides go down in a huge implosion. The Pharisee and those that
followed them have tried to modify these simple origins of Moses God using
much words of spirituality. But the inner core of Moses is one of the natural
order of volcanic effects and this has both a warlike vengeful God connotation
as well as one of Satan. These cover-ups are the root of all the massive
wars the people of this world have been drawn.
-
- The ultimate antithesis is fluoride sets up the ultimate
contrast between reasons for communism's ban on religion and those that
pillory people with religion for power and control. Lost between the paradigms
is the factor of good and the real God. The real dialectics Jesus spoke
of are missing. The fact is that in the US, the war on communism used the
church. The catharsis that exposes all is the study of fluoride connections
to Egypt, the biblical narratives of Moses, and Jesus objections toward
these spiritual words that attempted to conceal the real story. It is a
story that most of the Jews that know Torah and Talmud know well.
-
- It gets down to a method for the NWO, where the God of
Moses is slipped into the bible narratives and not explained well to the
Christian masses. It is explained so poorly that most think the God of
Moses, the nationalistic God of the Jews, and the God of Jesus are one
in the same. It is this omission and the conspiracy of silence tied to
it, that is part of the Jews thinking their subtle take over methods are
acceptable to organized religion in the US and the world. The war on communism
has been used by the power seeking methods of the Jews to take control
of the US.
-
- It is ultimately the evangelical uses of spirituality
to embellish these issues in such a way as to confuse and obfuscate them.
It is done because these evangelicals are more interested in loosing a
little money from the pocketbooks of their parishioners, more-so than telling
the full story of correct spiritually and incorrect conspiracies of silence
of the whole story. The real story is the church, as an ultimate weapon
against communism and a tool for the Jews conquest, has presented a lie
and a conspiracy of silence.
-
- These are the methods of power and control using the
false concepts presented by those of religion. This is the story of how
science met religion in the Manhattan Project and beyond---and how the
real message of Jesus was introduced to most in the US National Security
system. Many of the very same interests that covered up the dangers of
fluoride were the same players that cover up the reasons JFK was assassinated.
It is the strong overlap of fluoride-related issues into Jewish / Torah
religion factors and how these influenced the church and the war on Communism
that played the essential role in the death of JFK. This is why Oak Ridge's
Y-12 plant played a preeminent role in the assassination of JFK by networking
with Jacob Rubenstein, AKA Jack Ruby.
-
- The war against communism is a no win when the best defenses
are based upon a lie, and likewise a democracy built upon the false concepts
of religion is doomed to be taken from within, a people exploited. Likewise,
the church cannot be called a Church based in Christ, unless these truths
become known. The Church has become a part of the Conspiracy of Silence
that leads the flock astray. The only way to proceed now is all the facts
on the table, the end of the secrecy, and return to the concepts of equality
to all the people.
-
- I hope that each of you have enjoyed these insights into
the inner secrets of the Manhattan Project and the health effects of fluorides.
May these secrets unleashed here set all free to enter a kinder and gentler
time.
-
- _____
-
- REFERENCE 1
-
- http://www.newscientist.com/hottopics/tech/article.jsp?id=99993669&sub=Medical
-
-
- Lucky discovery uncovers cancer-proof mouse By Shaoni
Bhattacharya
-
- A cancer-proof mouse, which can survive being injected
with any number of cancer cells, has been discovered by US scientists.
The discovery of the resistant mouse could pave the way for future gene
or drug therapies if the mechanism by which it fights cancer can be understood
-
- Researchers at the Wake Forest University School of Medicine
in North Carolina have now bred a colony of 700 cancer-proof mice from
the resistant male they stumbled across while doing other experiments.
-
- Doctors have known for many years that in rare cases,
cancers can mysteriously clear up of their own accord. But this is the
first time such cancer-killing ability has been shown to be genetic.
-
- "The power of this resistance seems to be unlimited,"
said biochemist Zheng Cui, the study leader. "You can give them many,
many tumour cells and the mice get rid of them."
-
- "This is at a preliminary stage, but very promising,"
adds pathologist Mark Willingham, another member of the team. "Our
hope is that, some day, this will have an impact on human cancer."
-
- Seven generations
-
- The scientists discovered the original cancer-proof mouse
by luck during experiments in which mice were injected with soft tissue
cancers, called sarcomas. Despite repeated injections, one mouse did not
develop cancer. When this mouse bred with a normal mouse, some of their
offspring were resistant. And these resistant mice were also able to confer
resistance, for at least seven generations. "The resistance appears
to be caused by just one gene, or a cluster of closely related genes,"
Cui told New Scientist.
-
- The cancer-killing ability of the mice was unusually
consistent with different types of cancer. "What's surprising is it
appears these mice are able to recognise something in common to all cancer
cell lines," said Cui. "Usually it's difficult to find a common
theme."
-
- Willingham told New Scientist that the cancer cells are
killed by the mice in a "somewhat novel" way. The body's usual
first line of defence against invaders - white blood cells called T-cells
- were not employed. Instead the body's innate immune system, consisting
of cells like neutrophils and macrophages, attacked the tumour cells and
ruptured them.
-
- Previous mice bred so that their immune systems could
beat cancer went on the develop autoimmune diseases, but that did not happen
with these mice. One significant puzzle that remains is how the mice detect
the cancer cells in the first place. Cui speculates that some kind of diffusible
factor from the tumour may betray the deadly cells.
-
- Paul Ko Ferrigno, a cancer biologist at the MRC's cancer
cell research unit in Cambridge, UK, calls the findings "very tantalising".
"I'm intrigued and excited. If they can pin down what the immune basis
for resistance to cancer is it should be straightforward to train a patient's
immune system to do the same," he told New Scientist. Although they
are preliminary, the study's findings have "huge potential",
he says.
-
- The top priority now, says Willingham, is to identify
the mouse gene responsible for the resistance. "Because of the Human
Genome Project, we could then look for a correlate gene in humans,"
he said.
-
- Journal reference: Proceedings of the National Academy
of Sciences: (doi/10.1073/pnas.1031601100)
-
-
-
- ----------------
-
- REFERENCE 2:
-
- http://www.eurekalert.org/pub_releases/2002-04/jhmi-mbh042502.php
-
- Manganese blocks HIV replication; Lab finding points
to potential new class of HIV treatments
-
- Johns Hopkins scientists have found that simply increasing
manganese in cells can halt HIV's unusual ability to process its genetic
information backwards, providing a new way to target the process's key
driver, an enzyme called reverse transcriptase.
-
- By measuring DNA produced by a related reverse transcriptase
in yeast, the Hopkins team discovered that higher than normal levels of
manganese, caused by a defective gene, dramatically lowered the enzyme's
activity. The scientists then proved that HIV's reverse transcriptase responds
to manganese in the same way. Hopkins graduate student Eric Bolton determined
that the defective gene is PMR1, whose protein carries both manganese and
calcium out of cells. Using special yeast developed by others at Hopkins,
he discovered that manganese stops reverse transcriptase, the team reports
in the April 26 issue of Molecular Cell.
-
- "These results really point to a never-before-proposed
way to try to stop HIV in its tracks -- that simply manipulating concentrations
of a metal, manganese, can have a profound effect on reverse transcriptase,"
says Jef Boeke, Ph.D., professor of molecular biology and genetics at the
school's Institute for Basic Biomedical Sciences. "We expect the human
equivalent of PMR1 could be a good target for developing new drugs against
HIV."
-
- Retroviruses like HIV use reverse transcriptase to make
copies of their DNA from RNA, the opposite of how genetic information is
usually processed in cells. Each retrovirus has a distinct version of the
enzyme, identical in function but different in form and sequence, says
Boeke, also a professor of oncology.
-
- The scientists found that each reverse transcriptase
they studied has at least two places where manganese and the similar metal
magnesium can "dock." Having these spots filled with the right
metal is crucial for the enzyme's activity -- its ability to read a particular
set of RNA, the scientists learned. When the metals' balance is out of
whack, the enzyme doesn't work properly, they report.
-
- "Most reverse transcriptases we studied prefer to
bind magnesium. At the very least they were more active when magnesium
was bound to them," says Boeke. "But a little extra manganese
changes the activity of the enzyme."
-
- Normally, charged magnesium ions outnumber those of manganese
by the thousands inside cells. Having just three times more manganese than
normal can cut the activity of HIV's reverse transcriptase in half, the
scientists report, even though there's still much more magnesium.
-
- http://www.doewatch.com/f.html
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