- Endotracheal intubation: a procedure by which a tube
is inserted through the mouth down into the trachea (the large airway from
the mouth to the lungs).
- Spinal anaesthesia: used during caesarians, hernia repairs
and other operations below the navel.
- A peripheral nerve block: a medical procedure that involves
administration of a dose of local anesthetic usually into either your arm,
hand, leg, or ankle region.
- Anesthesia And Non-Conventional Transmissible Agents
(Or Prion Diseases)
- JP Estebe Annales Francaises D'Anesthesie Et de Reanimation
Volume 16 ï Issue 8 1997 16:955-63
- Abstract The transmissible spongiform encephalopathies
(TSE) represent a group of neurodegenerative diseases with lethal outcome.
They include Creutzfeldt-Jakob disease (CJD) and kuru, among others in
humans, scrapie in sheep and spongiform encephalopathy in cattle (bovine
spongiform encephalopathy: BSE)...
- A new variant clinicopathological type of CJD (nvCJD)
has been reported. The nvCJD has strain characteristics distinct from other
types of CJD, close to those of BSE transmitted (studies with intracerebral
inoculation), consistent with BSE being the source of this new disease...
- It has been suggested that CJD might be transmitted by
blood products derived from patients with CJD during the prodromal [precursory]
- For the most part of conformational changes of PrPc,
the remarkable resistance of the infectious agent (PrP alone or combined)
to ordinary sterilising procedures is a major problem. Because of this
resistance, current recommendations are to recognize patients at risks
and to use disposable medical devices. This is particularly true in anaesthesia
during endotracheal intubation, spinal anaesthesia, and to a lesser extent
with peripheral nerve blocks.
- All instruments used for patients with CJD must be destroyed.
The economic consequences of these measures have highlighted the essential
importance of an early diagnosis.