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Toronto Doctors Baffled How
SARS Infected US Man

By Rajiv Sekhri
6-11-3


TORONTO (Reuters) - Toronto doctors said on Wednesday they were mystified by how the SARS virus spreads after a U.S. man caught it while visiting a ward in a Toronto geriatric hospital thought to be free of the deadly illness.
 
Infection-control specialists said the baffling transmission could be the first of its kind in Toronto. And after teams here battled SARS for three months, the outbreak also heightens fear and confusion as they probe 12 new possible SARS cases just east of the city.
 
A North Carolina man developed SARS more than a week after he left Toronto in mid-May. A patient in the same room the American had visited was later diagnosed with severe acute respiratory syndrome. The patient had been transferred to the geriatric hospital on May 15 from a Toronto facility where the SARS virus had lingered unnoticed for two weeks.
 
What is puzzling, doctors say, is why the transferred patient who had been exposed to the virus didn't show even mild SARS symptoms -- high fever, difficulty in breathing, dry cough -- and how he could have spread the virus to the U.S. visitor but not other patients and nurses.
 
"It defies imagination as to what happened," said Dr. Donald Low, chief of microbiology at Mount Sinai Hospital in Toronto, who is one of the leaders in the battle against SARS.
 
"I think we have to accept the fact that (the U.S. visitor) got SARS in Toronto and that most likely he got it in a health-care facility because that is where he visited, and there happened to be SARS cases that eventually showed up in the same room," Low said in an interview.
 
"But we don't feel comfortable putting the whole story together with what we know about this disease to date," Low said, adding that the SARS outbreak is the "most unusual and difficult challenge" he has faced in his 25 years of combating infectious diseases.
 
Dr. Alan Bernstein, president of the Canadian Institutes of Health Research (CIHR), said it is difficult to build a "scientific story" around one such case.
 
But he said a transmission such as this raises questions about whether the quarantine should be raised from 10 days for those who may have been exposed to the virus and the need for more sensitive testing.
 
There is no diagnostic test for SARS yet and no vaccine.
 
The disease has killed 33 people in the Toronto area, the only place outside of Asia hit hard by the virus, which originated in southern China and has spread to about 30 countries through travelers.
 
Health officials on Wednesday were planning to send up to a 1,000 people in Whitby, east of Toronto, into quarantine after 12 patients at dialysis clinic developed SARS-like symptoms. Officials are investigating this new possible cluster, which, if confirmed, would be the Toronto area's third outbreak of SARS. The first one lasted from mid-March to mid-April.
 
The disease resurfaced in late May, more than a month after no new case had been reported, crushing hopes the city had the virus under control.
 
Doctors are still learning more about the virus but say more research is needed.
 
Dr. Bhagirath Singh, scientific director of the CIHR's Institute of Infection and Immunity, said: "We are learning the virus can survive three hours, and now people believe it can survive up to three days. Do we have answers? The answer is, no."
 
Worldwide, SARS has killed about 780 people and infected more than 8,400. In the Toronto area, where more than 4 million people live, there are 64 probable SARS cases. Twenty three people were in critical condition on Tuesday and another 260 were being monitored for infection.
 
Copyright © 2003 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon.
 
 
 
Comment
 
From Frances
6-11-3
 
Welll duh.... Lessee now.... This geriatric ward, is INside the hospital right? And we are assuming it's NOT right beside the front door (as most aren't). So we have to go down corridors and maybe open a few doors along the way and perhaps go upstairs or take an elevator (both of which have things we normally touch to use - ie: handrails or buttons) and then there's more corridors and doors to open etc... Til finally we arrive at the room in question. None of these surfaces would have SARS on them though cuz we know the virus dies the moment it leaves the body right? Yeah BS. How many weeks or days is it that it survives on surfaces outside the body? Forgot.... But duh.... I swear to God I don't know how any of these people got degrees in anything let alone medicine!


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