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Neuramidase In SARS? -
None Known In
Any Coronavirus
From Dr. Robert E. Lee PhD
rboblee@mchsi.com
4-28-3

Jeff

Following is information suggesting neuramidase in SARS. I am providing the multiple sequence alignment below and the phylogeny (in 3 different views) are attached as .pdf files. The significance of neuramidase in SARS is this:

1. There is NO KNOWN neuramidase in any known coronavirus.

2. Neuramidase is found in influenza viruses.

3. SARS appears possibly to be an influenza orthomyxovirus - coronavirus hybrid.

4. Neuramidase cleaves sialic acid inside cells and mediates viral attachment to the respiratory epithelium of the host and consequent infection of susceptible cells.

5. This neuramidase, if, in fact, that is what it is, is not like any known neuramidase.

6. If this is, in fact, neuramidase, this would be the first known appearance of neuramidase in any coronavirus and would further suggest that SARS is an orthomyxovirus - coronavirus hybrid. Interestingly, the hemagglutinin-esterase in SARS shows some relationship to a Type C Influenza as well -- but SARS IS a coronavirus... a very weird coronavirus... but still a coronavirus.

7. If SARS coronavirus is a naturally occurring coronavirus, efforts should be directed toward discovery of other orthymyxovirus-coronavirus hybrid-like viruses. There may be sufficient evidence developed in time to reveal that SARS is not a true coronavirus nor a true orthomyxovirus and so become an entirely new species of virus all together.

neuramidaseSARS1.pdf

neuramidaseSARS2.pdf

neuramidaseSARS3.pdf

Data follows:

 

The neuramidase is likely here:
25253..26077
/codon_start=1
/evidence=not_experimental
/product="putative uncharacterized protein"
/protein_id="<http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_828852.1>NP_828852.1"
/db_xref="GI:29836497"
/translation="MDLFMRFFTLGSITAQPVKIDNASPASTVHATATIPLQASLPFG
WLVIGVAFLAVFQSATKIIALNKRWQLALYKGFQFICNLLLLFVTIYSHLLLVAAGME
AQFLYLYALIYFLQCINACRIIMRCWLCWKCKSKNPLLYDANYFVCWHTHNYDYCIPY
NSVTDTIVVTEGDGISTPKLKEDYQIGGYSEDRHSGVKDYVVVHGYFTEVYYQLESTQ
ITTDTGIENATFFIFNKLVKDPPNVQIHTIDGSSGVANPAMDPIYDEPTTTTSVPL"
CLUSTAL W (1.82) multiple sequence alignment
 
 
gi|21636414|gb|AAM69980.1|AF45 -----------------------MQIAILATTVTLHFKQNECSIPAKNQV 27
gi|21636376|gb|AAM69959.1|AF45 ---NQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQNECSIPAKNQV 47
gi|21636383|gb|AAM69963.1|AF45 MNPNQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQNECSIPAKNQV 50
gi|21636432|gb|AAM69990.1|AF45 -----------------------MQIAILATTVTLHFKQNECSIPAKNQV 27
gi|21636453|gb|AAM70002.1|AF45 MNPNQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQNECSIPAKNQV 50
gi|21636396|gb|AAM69970.1|AF45 MNPNQKIITIGSVSLTIATVCFLMQIAILATTVTLHFKQNECSIPAKNQV 50
gi|29832477|ref|NP_827111.1| --------------------------------------------------
gi|29609596|dbj|BAC73646.1| --------------------------------------------------
gi|29832149|ref|NP_826783.1| -------------------------MSVRSRTTLLAAAVGLVTALAVTGT 25
gi|29609267|dbj|BAC73318.1| -------------------------MSVRSRTTLLAAAVGLVTALAVTGT 25
gi|4007675|emb|CAA22361.1| -------------------------MPPRTRR-PFWLALATSCALAVSSP 24
gi|21224859|ref|NP_630638.1| -------------------------MPPRTRR-PFWLALATSCALAVSSP 24
gi|7481072|pir||T34999 -------------------------MPPRTRR-PFWLALATSCALAVSSP 24
gi|29836497|gb|NP_828852.1|NP_ --------------------------------------------------
                                                                                    
 
gi|21636414|gb|AAM69980.1|AF45 MPCEPIIAEGPKAVDYRSWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 77
gi|21636376|gb|AAM69959.1|AF45 MPCEPIIAEGPKAVDYRSWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 97
gi|21636383|gb|AAM69963.1|AF45 VPCEPIIAEGPKAVDYRSWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 100
gi|21636432|gb|AAM69990.1|AF45 VPCEPIIAEGPKAVDYRSWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 77
gi|21636453|gb|AAM70002.1|AF45 VPCEPTIAERPKAADYRIWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 100
gi|21636396|gb|AAM69970.1|AF45 VPCEPTIAERPKAVDYRIWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTR 100
gi|29832477|ref|NP_827111.1| ------------MTEASTPFRGGRE--GYASYRIPAVVATGVGTLLAFCE 36
gi|29609596|dbj|BAC73646.1| ------------MTEASTPFRGGRE--GYASYRIPAVVATGVGTLLAFCE 36
gi|29832149|ref|NP_826783.1| AGPAAAAPPPSRGCTSSVPYTAGQY--GYDTYRIPATLRTRAGTLLAFAE 73
gi|29609267|dbj|BAC73318.1| AGPAAAAPPPSRGCTSSVPYTAGQY--GYDTYRIPATLRTRAGTLLAFAE 73
gi|4007675|emb|CAA22361.1| FPAHARPGDRAPAFGEQVLFDAARDPGGYACFRIPAIVRTTDGTLLAFAE 74
gi|21224859|ref|NP_630638.1| FPAHARPGDRAPAFGEQVLFDAARDPGGYACFRIPAIVRTTDGTLLAFAE 74
gi|7481072|pir||T34999 FPAHARPGDRAPAFGEQVLFDAARDPGGYACFRIPAIVRTTDGTLLAFAE 74
gi|29836497|gb|NP_828852.1|NP_ -------------------MDLFMRFFTLGSITAQPVKIDNASPASTVHA 31
. . 
 
gi|21636414|gb|AAM69980.1|AF45 ETYVSCDTSKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMSELGVPFH 127
gi|21636376|gb|AAM69959.1|AF45 ETYVSCDTSKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMSELGVPFH 147
gi|21636383|gb|AAM69963.1|AF45 ETYVSCDTSKCYQFALGQGTTLDNKHSNGTIHDRTPHRTLLMSELGVPFH 150
gi|21636432|gb|AAM69990.1|AF45 EPYVSCDTSKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMSELGVPFH 127
gi|21636453|gb|AAM70002.1|AF45 EPYVSCETSKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMSELGVPFH 150
gi|21636396|gb|AAM69970.1|AF45 EPYVSCETSKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMSELGVPFH 150
gi|29832477|ref|NP_827111.1| GRVDSAHDHGNIDIVLKRSGDGGRTWGPLQAVAKNGDNLAGNPAPVVLD- 85
gi|29609596|dbj|BAC73646.1| GRVDSAHDHGNIDIVLKRSGDGGRTWGPLQAVAKNGDNLAGNPAPVVLD- 85
gi|29832149|ref|NP_826783.1| GRRGGAGDTGNIDVVLRRSFDGGCAWGPLTVVAAGRGDTRGNPAPVVDSR 123
gi|29609267|dbj|BAC73318.1| GRRGGAGDTGNIDVVLRRSFDGGCAWGPLTVVAAGRGDTRGNPAPVVDSR 123
gi|4007675|emb|CAA22361.1| GRVLDCADDGDIDIVLRRSLDGGRTWGPLRVVNDGGGDTHGNPAPVVDRA 124
gi|21224859|ref|NP_630638.1| GRVLDCADDGDIDIVLRRSLDGGRTWGPLRVVNDGGGDTHGNPAPVVDRA 124
gi|7481072|pir||T34999 GRVLDCADDGDIDIVLRRSLDGGRTWGPLRVVNDGGGDTHGNPAPVVDRA 124
gi|29836497|gb|NP_828852.1|NP_ TATIPLQASLPFGWLVIGVAFLAVFQSATKIIALN-KRWQLALYKGFQFI 80
: . .  
 
gi|21636414|gb|AAM69980.1|AF45 LGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSIGS 176
gi|21636376|gb|AAM69959.1|AF45 LGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSIGS 196
gi|21636383|gb|AAM69963.1|AF45 LGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSIGS 199
gi|21636432|gb|AAM69990.1|AF45 LGIKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSIGS 176
gi|21636453|gb|AAM70002.1|AF45 LGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSISS 199
gi|21636396|gb|AAM69970.1|AF45 LGTKQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYD-GMLVDSISS 199
gi|29832477|ref|NP_827111.1| TGRVLLVHVRSAAGASEDAILRGKVKAADGRRVWVQHSDDDGLTWSGPRE 135
gi|29609596|dbj|BAC73646.1| TGRVLLVHVRSAAGASEDAILRGKVKAADGRRVWVQHSDDDGLTWSGPRE 135
gi|29832149|ref|NP_826783.1| TGRIVLVTSYNGGAVTEAQIMRGEVTPEQSRRVFVQTSRDDGRHFSAPRD 173
gi|29609267|dbj|BAC73318.1| TGRIVLVTSYNGGAVTEAQIMRGEVTPEQSRRVFVQTSRDDGRHFSAPRD 173
gi|4007675|emb|CAA22361.1| TGRVLLLETYNAGRTDS-----ADCAVPCARVPHVQHSDDGGRTWSAPRD 169
gi|21224859|ref|NP_630638.1| TGRVLLLETYNAGRTDS-----ADCAVPCARVPHVQHSDDGGRTWSAPRD 169
gi|7481072|pir||T34999 TGRVLLLETYNAGRTDS-----ADCAVPCARVPHVQHSDDGGRTWSAPRD 169
gi|29836497|gb|NP_828852.1|NP_ CNLLLLFVTIYS----------HLLLVAAGMEAQFLYLYALIYFLQCIN- 119
. : . .   
 
gi|21636414|gb|AAM69980.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKADTRILFIK---EGKIAH 223
gi|21636376|gb|AAM69959.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKADTRILFIK---EGKIAH 243
gi|21636383|gb|AAM69963.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKANTRILFIK---EGKIAH 246
gi|21636432|gb|AAM69990.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKADTRILFIK---EGKIAH 223
gi|21636453|gb|AAM70002.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKADTRILFIK---EGKIAH 246
gi|21636396|gb|AAM69970.1|AF45 WSQNILRTQESECVCINGTCTVVMTDGSASGKADTRILFIK---EGKIAH 246
gi|29832477|ref|NP_827111.1| ITGQVRKANWR-WYATTPGHALQLTTG----RVVVPGNH-----TVPPTG 175
gi|29609596|dbj|BAC73646.1| ITGQVRKANWR-WYATTPGHALQLTTG----RVVVPGNH-----TVPPTG 175
gi|29832149|ref|NP_826783.1| ITAQVKPANWR-WYATGPGHAVALTRGPHAGRLVVPANHS----AAPPEG 218
gi|29609267|dbj|BAC73318.1| ITAQVKPANWR-WYATGPGHAVALTRGPHAGRLVVPANHS----AAPPEG 218
gi|4007675|emb|CAA22361.1| LSPEILPPDWNSWYATGPVHGVQLTGGAHPGRLVVGVNAETWDGERSEMG 219
gi|21224859|ref|NP_630638.1| LSPEILPPDWNSWYATGPVHGVQLTGGAHPGRLVVGVNAETWDGERSEMG 219
gi|7481072|pir||T34999 LSPEILPPDWNSWYATGPVHGVQLTGGAHPGRLVVGVNAETWDGERSEMG 219
gi|29836497|gb|NP_828852.1|NP_ -ACRIIMRCWLCWKCKSKNP------------------------------ 138
: .: .                                  
 
gi|21636414|gb|AAM69980.1|AF45 ISPLSGSAQHIEECSCYPQYSSVRCVCRDNWKGSN--RPIIDINMADYSI 271
gi|21636376|gb|AAM69959.1|AF45 ISPLSGSAQHIEECSCYPQYSSVRCVCRDNWKGSN--RPIIDINMADYSI 291
gi|21636383|gb|AAM69963.1|AF45 ISPLSGSAQHIEECSCYPQYSSVRCVCRDNWKGSN--RPIIDINMADYSI 294
gi|21636432|gb|AAM69990.1|AF45 ISPLSGSAQHIEECSCYPQYSNVRCVCRDNWKGSN--RPIIDINMADYSI 271
gi|21636453|gb|AAM70002.1|AF45 ISPLSGSAQHIEECSCYPQYSNVRCVCRDNWKGSN--RPIIDINMADYSI 294
gi|21636396|gb|AAM69970.1|AF45 ISPLSGSAQHIEECSCYPQYSNVRCVCRDNWKGSN--RPIIDINMADYSI 294
gi|29832477|ref|NP_827111.1| -TDNGTEAKYNSGHC--LLSDDRGASWYLGYLDEN---TNGYIN--VNET 217
gi|29609596|dbj|BAC73646.1| -TDNGTEAKYNSGHC--LLSDDRGASWYLGYLDEN---TNGYIN--VNET 217
gi|29832149|ref|NP_826783.1| SADTGREARYYGAHA--IYSDDGGLTWRLGFVDDS---YDGVDN--ANEN 261
gi|29609267|dbj|BAC73318.1| SADTGREARYYGAHA--IYSDDGGLTWRLGFVDDS---YDGVDN--ANEN 261
gi|4007675|emb|CAA22361.1| VPPAGGWGRVTANHAALVVSDDGGEHWRTGATDTWPVAADGTFRQKPSEL 269
gi|21224859|ref|NP_630638.1| VPPAGGWGRVTANHAALVVSDDGGEHWRTGATDTWPVAADGTFRQKPSEL 269
gi|7481072|pir||T34999 VPPAGGWGRVTANHAALVVSDDGGEHWRTGATDTWPVAADGTFRQKPSEL 269
gi|29836497|gb|NP_828852.1|NP_ -----------------LLYDAN---YFVCWHTHN----------YDYCI 158
.                            
 
gi|21636414|gb|AAM69980.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 321
gi|21636376|gb|AAM69959.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 341
gi|21636383|gb|AAM69963.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 344
gi|21636432|gb|AAM69990.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 321
gi|21636453|gb|AAM70002.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 344
gi|21636396|gb|AAM69970.1|AF45 DSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDDGNDVWM 344
gi|29832477|ref|NP_827111.1| TATELPDGRVYFNTRN-DSPSPGNRADAYSKDG-----GKTLVKPFRPQA 261
gi|29609596|dbj|BAC73646.1| TATELPDGRVYFNTRN-DSPSPGNRADAYSKDG-----GKTLVKPFRPQA 261
gi|29832149|ref|NP_826783.1| AAAELPDGRLYFSARDQNGTSAGNRLDTYSGDG-----AQTLDRPYAVQP 306
gi|29609267|dbj|BAC73318.1| AAAELPDGRLYFSARDQNGTSAGNRLDTYSGDG-----AQTLDRPYAVQP 306
gi|4007675|emb|CAA22361.1| TLTERADGALLVSGREENGTDPGHRTQALSRDG-----GDSFAAPFRALP 314
gi|21224859|ref|NP_630638.1| TLTERADGALLVSGREENGTDPGHRTQALSRDG-----GDSFAAPFRALP 314
gi|7481072|pir||T34999 TLTERADGALLVSGREENGTDPGHRTQALSRDG-----GDSFAAPFRALP 314
gi|29836497|gb|NP_828852.1|NP_ PYNSVTDTIVVT---EGDGISTPKLKEDYQIGG----------------- 188
. : : :. .. : : . *                
 
gi|21636414|gb|AAM69980.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 370
gi|21636376|gb|AAM69959.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 390
gi|21636383|gb|AAM69963.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 393
gi|21636432|gb|AAM69990.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 370
gi|21636453|gb|AAM70002.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 393
gi|21636396|gb|AAM69970.1|AF45 GRTISKDSRSGYETFK-VIDGWATANSKSQTNRQVIVDNNNWSGYSGIFS 393
gi|29832477|ref|NP_827111.1| GLT-TPVVQGSVLQLR-DPDLLLYSGPADPAFRALMTVRASADGGTTWRT 309
gi|29609596|dbj|BAC73646.1| GLT-TPVVQGSVLQLR-DPDLLLYSGPADPAFRALMTVRASADGGTTWRT 309
gi|29832149|ref|NP_826783.1| TLNDVPVVQGSVLQLTGNGAPLLFSGPSVPTARRSMAIRRSEDGGGTFVT 356
gi|29609267|dbj|BAC73318.1| TLNDVPVVQGSVLQLTGNGAPLLFSGPSVPTARRSMAIRRSEDGGGTFVT 356
gi|4007675|emb|CAA22361.1| DLY-APQVQGAVLRLG---NRILLSAPADPDRRRTMTVRSSRDGGATWDS 360
gi|21224859|ref|NP_630638.1| DLY-APQVQGAVLRLG---NRILLSAPADPDRRRTMTVRSSRDGGATWDS 360
gi|7481072|pir||T34999 DLY-APQVQGAVLRLG---NRILLSAPADPDRRRTMTVRSSRDGGATWDS 360
gi|29836497|gb|NP_828852.1|NP_ ---YSEDRHSGVKDYV-VVHGYFTEVYYQLESTQITTDTGIENATFFIFN 234
:.. . .. .
 
gi|21636414|gb|AAM69980.1|AF45 VENKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 418
gi|21636376|gb|AAM69959.1|AF45 VENKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 438
gi|21636383|gb|AAM69963.1|AF45 VENKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 441
gi|21636432|gb|AAM69990.1|AF45 VENKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 418
gi|21636453|gb|AAM70002.1|AF45 VETKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 441
gi|21636396|gb|AAM69970.1|AF45 VENKGCIN--RCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWP 441
gi|29832477|ref|NP_827111.1| AHPLDGLP---AAYSDLVRVDQDTVGLLYET-------GDFGAYETITFR 349
gi|29609596|dbj|BAC73646.1| AHPLDGLP---AAYSDLVRVDQDTVGLLYET-------GDFGAYETITFR 349
gi|29832149|ref|NP_826783.1| VKTLSALP---AAYSDLVQVSATKVGILYET-------GVAGPYDSIEFR 396
gi|29609267|dbj|BAC73318.1| VKTLSALP---AAYSDLVQVSATKVGILYET-------GVAGPYDSIEFR 396
gi|4007675|emb|CAA22361.1| ADRGTVVTRDWAGYSDLVTVDDDTVGLLYEG-------GKTDARDEIRFA 403
gi|21224859|ref|NP_630638.1| ADRGTVVTRDWAGYSDLVTVDDDTVGLLYEG-------GKTDARDEIRFA 403
gi|7481072|pir||T34999 ADRGTVVTRDWAGYSDLVTVDDDTVGLLYEG-------GKTDARDEIRFA 403
gi|29836497|gb|NP_828852.1|NP_ KLVKDPPN------VQIHTIDGSS--------------GVANPAMDPIYD 264
:: * .. :
 
gi|21636414|gb|AAM69980.1|AF45 DGANI--------------------------------------------- 423
gi|21636376|gb|AAM69959.1|AF45 DGA----------------------------------------------- 441
gi|21636383|gb|AAM69963.1|AF45 DGANIDFMPI---------------------------------------- 451
gi|21636432|gb|AAM69990.1|AF45 DGANI--------------------------------------------- 423
gi|21636453|gb|AAM70002.1|AF45 DGANIDFMPI---------------------------------------- 451
gi|21636396|gb|AAM69970.1|AF45 DGANIDFMPI---------------------------------------- 451
gi|29832477|ref|NP_827111.1| RIPVTALT------------------------------------------ 357
gi|29609596|dbj|BAC73646.1| RIPVTALT------------------------------------------ 357
gi|29832149|ref|NP_826783.1| RVPVGEL------------------------------------------- 403
gi|29609267|dbj|BAC73318.1| RVPVGEL------------------------------------------- 403
gi|4007675|emb|CAA22361.1| RLTADRLAPPRGPDPTTPDLAANAAPAAVLGGAAPTTDGAVGGALAFDGA 453
gi|21224859|ref|NP_630638.1| RLTADRLAPPRGPDPTTPDLAANAAPAAVLGGAAPTTDGAVGGALAFDGA 453
gi|7481072|pir||T34999 RLTADRLAPPRGPDPTTPDLAANAAPAAVLGGAAPTTDGAVGGALAFDGA 453
gi|29836497|gb|NP_828852.1|NP_ EPTTTTSVPL---------------------------------------- 274
.                                              
 
gi|21636414|gb|AAM69980.1|AF45 --------------------------------------------------
gi|21636376|gb|AAM69959.1|AF45 --------------------------------------------------
gi|21636383|gb|AAM69963.1|AF45 --------------------------------------------------
gi|21636432|gb|AAM69990.1|AF45 --------------------------------------------------
gi|21636453|gb|AAM70002.1|AF45 --------------------------------------------------
gi|21636396|gb|AAM69970.1|AF45 --------------------------------------------------
gi|29832477|ref|NP_827111.1| --------------------------------------------------
gi|29609596|dbj|BAC73646.1| --------------------------------------------------
gi|29832149|ref|NP_826783.1| --------------------------------------------------
gi|29609267|dbj|BAC73318.1| --------------------------------------------------
gi|4007675|emb|CAA22361.1| DDAVRLPYDGRLALGEGDFTASLWFRYSAADGEQPLLWMGGIGTTQPQVW 503
gi|21224859|ref|NP_630638.1| DDAVRLPYDGRLALGEGDFTASLWFRYSAADGEQPLLWMGGIGTTQPQVW 503
gi|7481072|pir||T34999 DDAVRLPYDGRLALGEGDFTASLWFRYSAADGEQPLLWMGGIGTTQPQVW 503
gi|29836497|gb|NP_828852.1|NP_ --------------------------------------------------
                                                                                    
 
gi|21636414|gb|AAM69980.1|AF45 --------------------------------------------------
gi|21636376|gb|AAM69959.1|AF45 --------------------------------------------------
gi|21636383|gb|AAM69963.1|AF45 --------------------------------------------------
gi|21636432|gb|AAM69990.1|AF45 --------------------------------------------------
gi|21636453|gb|AAM70002.1|AF45 --------------------------------------------------
gi|21636396|gb|AAM69970.1|AF45 --------------------------------------------------
gi|29832477|ref|NP_827111.1| --------------------------------------------------
gi|29609596|dbj|BAC73646.1| --------------------------------------------------
gi|29832149|ref|NP_826783.1| --------------------------------------------------
gi|29609267|dbj|BAC73318.1| --------------------------------------------------
gi|4007675|emb|CAA22361.1| LRAEPDAGRVQGLITARDGATAPRSAWVRTDRAYDDGRWHRLTLRRGGGR 553
gi|21224859|ref|NP_630638.1| LRAEPDAGRVQGLITARDGATAPRSAWVRTDRAYDDGRWHRLTLRRGGGR 553
gi|7481072|pir||T34999 LRAEPDAGRVQGLITARDGATAPRSAWVRTDRAYDDGRWHRLTLRRGGGR 553
gi|29836497|gb|NP_828852.1|NP_ --------------------------------------------------
                                                                                    
 
gi|21636414|gb|AAM69980.1|AF45 --------------------------------------------------
gi|21636376|gb|AAM69959.1|AF45 --------------------------------------------------
gi|21636383|gb|AAM69963.1|AF45 --------------------------------------------------
gi|21636432|gb|AAM69990.1|AF45 --------------------------------------------------
gi|21636453|gb|AAM70002.1|AF45 --------------------------------------------------
gi|21636396|gb|AAM69970.1|AF45 --------------------------------------------------
gi|29832477|ref|NP_827111.1| --------------------------------------------------
gi|29609596|dbj|BAC73646.1| --------------------------------------------------
gi|29832149|ref|NP_826783.1| --------------------------------------------------
gi|29609267|dbj|BAC73318.1| --------------------------------------------------
gi|4007675|emb|CAA22361.1| LTLFVDGSAAADAADVPGSVSRNSPFGVHIGERMDGRARFTGAVDDVQVW 603
gi|21224859|ref|NP_630638.1| LTLFVDGSAAADAADVPGSVSRNSPFGVHIGERMDGRARFTGAVDDVQVW 603
gi|7481072|pir||T34999 LTLFVDGSAAADAADVPGSVSRNSPFGVHIGERMDGRARFTGAVDDVQVW 603
gi|29836497|gb|NP_828852.1|NP_ --------------------------------------------------
                                                                                    
 
gi|21636414|gb|AAM69980.1|AF45 ---------------------------------------------
gi|21636376|gb|AAM69959.1|AF45 ---------------------------------------------
gi|21636383|gb|AAM69963.1|AF45 ---------------------------------------------
gi|21636432|gb|AAM69990.1|AF45 ---------------------------------------------
gi|21636453|gb|AAM70002.1|AF45 ---------------------------------------------
gi|21636396|gb|AAM69970.1|AF45 ---------------------------------------------
gi|29832477|ref|NP_827111.1| ---------------------------------------------
gi|29609596|dbj|BAC73646.1| ---------------------------------------------
gi|29832149|ref|NP_826783.1| ---------------------------------------------
gi|29609267|dbj|BAC73318.1| ---------------------------------------------
gi|4007675|emb|CAA22361.1| NSALTDTEIAAGVPPAAGRSTVLHLPLDRVDEAAADTGGSTDTGG 648
gi|21224859|ref|NP_630638.1| NSALTDTEIAAGVPPAAGRSTVLHLPLDRVDEAAADTGGSTDTGG 648
gi|7481072|pir||T34999 NSALTDTEIAAGVPPAAGRSTVLHLPLDRVDEAAADTGGSTDTGG 648
gi|29836497|gb|NP_828852.1|NP_ ---------------------------------------------

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