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Is SARS Mutating Into
A Relatively Harmless Virus?

From Patricia Doyle, PhD
dr_p_doyle@hotmail.com
4-15-3


Hello Jeff - I believe, and have stated over the past week or so, that SARS will probably mutate into a harmless form or exhibit symptoms similar to that of a cold.
 
Of course, the EXPERTS are all "scratching" their heads on this one, i.e. the fact that SARS cases in the US have not been as severe as elsewhere in the world. The US is one of the latest "comers" to the SARS outbreak.
 
If I am correct, and SARS is caused by a manmade pathogen, we can expect to see it mutate extremely rapidly. I also believe that the Chinese were actually "playing" with the coronavirus/paramyxovirus and whatever else is in the genetic makeup of the virus. I believe that they were in the initial stage of a "chimeravirus" program. I think that this was the reason they chose a coronavirus. Large genome makes research easier. I think they also chose the paramyxoviruses for the purpose of learning how to combine and maintain infectivity and severity of symptoms and possibly to enable the virus to jump species barrier.
 
We know that coronaviruses RARELY jump species barrier. We identified animal coronaviruses only. i.e. viruses similar to mouse, bovine and avian coronavirus. There again, only similar and not the actual mouse, bovine and avian viruses. No human. The paramyxoviruses chosen were HUMAN and targeted at causing pneumonia. I would not be surprised if the intent was to develop a chimera and then infect prisoners with it and monitor spread and morbidity among the prisoners. Then, bury them, end of project thus retiring the pathogen that causes SARS with no one the wiser. What is it they say about the best laid plans of man?
 
Probably a lab worker took ill, or a nonprisoner and the rest, as they say, is history. A sick lab worker goes to hospital not knowing it is SARS and infects hospital staff, then doctor goes to Hong Kong takes ill, etc etc.
 
So, my best guess is that, because we have a chimeravirus, lab developed, and probably for the purpose of learning, the virus could be extremely unstable. I think that the choice of a coronavirus, shows that "they" were using it for a learning experience and not a bioweapon. The bioweapon would come later, with different virus family recombination, and after sufficient testing. Of course, I can not be sure, and I am not sure. I can only look at the virus chosen etc etc. Coronaviruses have the largest genome of all viruses and would be easier to use to learn about the chimera process.
 
Over the past few weeks, we look at the cases of SARS around the world and begin to notice that it is not as deadly as it was in Guangdong Province, Hong Kong etc. It now is less severe then Toronto.
 
The CDC will tell us that it is the quality US health care that is keeping morbidity down. Also, the well nourished population in the US, etc, etc. I don't think that CDC will theorize on an experimental chimeravirus developed and then escaping a Chinese lab. That would be very much politically incorrect. Bioweapons are quite unstable. Some have been programmed to make the agent a bit more stable. The fact of the matter is, that, especially in the case of chimeraviruses, we do not know how they will act in the environment. We know that the Russians developed Smallpox combined with Ebola, ergo Ebolapox, also VEEpox. We don't know how it would act in the environment. All we have is theory on paper. No previous human experience. I think that since SARS agent was not even intended for a bioweapon, its programming is such that it will be extremely unstable. My thought is that it will mutate harmless and probably, the most severe symptoms will ultimately be that of a cold.
 
If the CDC were to admit that the virus is "unraveling" and becoming less infective and/or less severe, than we have scientists coming foward with a theory that SARS could be a manmade pathogen.
 
What really worries me, is the fact that SARS appears to be a chimeravirus. The worry is that China may now have a Chimeravirus Program, in similar fashion to that of the former Soviet Union. It is also possible that some of the Soviet scientists had joined the Chinese bioweapons team. They obviously have the expertise to create Ebolapox, VEEpox etc and teaching this chimera method to the Chinese could be extremely dangerous for the world. Also of worry is the fact that NO ONE (in the who's who of science) is bringing up the possibility that the SARS agent is manmade. It seems like there is a gag order in progress when it comes to the origin of SARS. The ostrich syndrome will only allow for China to move foward with chimeravirus technology.
 
I do stress that the above is theory, my theory. I must also say that as we move foward through the SARS outbreak we start to find more puzzle pieces, that indicate SARS is a manmade virus. Could the fact that SARS is unstable and mutating either, to cold symptoms, or, to harmless be one more "dot" to connect with regard to the origin of the SARS outbreak?
 
I am taking everything into consideration, from the size of the genome, (ease of manipulating viral material) to the viruses that are recombinent, (coronavirus, paramyxovirus yet, re coronaviruses not matching any known to human and animal with some genetic material still unidentified) to adding paramyxoviruses for infectivity, jumping species barrier and severity of symptoms, to the present, the unstableness of the virus and I am trying to connecting all dots. Where does a bacteria fit the puzzle? There is evidence that an aerosolized form of Chlamydia (probably pneumonae) had infected some of the Chinese cases.
 
We may have sequenced the genome of the agent that causes SARS, but we have not completed identification of all genetic material within the virus genome, or found why it jumped species barrier, why it recombined with animal coronaviruses and human paramyxoviruses, why it does not act like ANY human or animal virus known to man. In short, we have not even found the origin of the virus. The mystery remains.
 
Again, I think that we shall see an unstable virus that will either mutate virulent or muate harmless with lower infectivity rate, lower mortality rate. It may be evidenced with symptoms no more than the common cold. I am hoping that it will mutate harmless, and it does appear that will be the case. My best guess is the reason we are starting to see less cases with lower mortality/morbidity rate, is because the virus is manmade.
 
Thank you
Patricia Doyle
 
 
Patricia A. Doyle, PhD
Please visit my "Emerging Diseases" message board at:
http://www.clickitnews.com/emergingdiseases/index.shtml
Zhan le Devlesa tai sastimasa
Go with God and in Good Health
 

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