- Note - As I said over 5 years ago, on this site and many
times on my program:
- the oral/body fluid transmission of infection and death
by prion is a reality. This
- newest study published in the New England Journal of
Medicine confirms that
- prions in the infected and dying are readily found in
nostrils. We already have
- proof prions are plentiful in tonsils, tongues and muscle
tissue of infected
- animals and people. Someday, a brave scientist will
confirm that prions are in
- all general body fluids...something that is more than
- Once again, I will state clearly: prions from BSE-infected
animals will also be found
- to be present in the body fluid called milk...meaning
all dairy products are susceptible
- to carrying prions. ALL of them. For obvious reasons,
no one is daring to do the
- research...or at least daring to publish the results.
Death by cheese, milk, ice
- cream and butter? We are at the end of the age of eating
- Meanwhile the USDA - in a laughable effort - is testing,
it claims, 3 out of every
- 1000 cattle sent to slaughter. If the USDA truly wanted
to search for mad
- cow infections it would check tens of thousands of cattle
in batches. Unfortunately,
- the beef and dairy industries are hardly likely to sanction
such common sense testing.
- They certainly don't want to tarnish their marketing
holy grail of happy people eating
- double cheese burgers and sporting milk moustaches.
- Shame on the dentists who have refused to discuss this
issue with me, and the
- thousands of other professionals who should know better.
All of them share an
- enormous responsibility and culpability. Patients infected
with Alzheimer's, CJD, vCJD
- and all the other code names for prion disease and death
show no symptoms during
- the early stages of infection.
- Every time one of these tragically-infected souls visits
a dentist in which reusable, invasive
- 'sterilized' instruments are used...and then subsequently
'sterilized' and reused...
- are quite clearly and logically potentially passing their
own deadly infections to multiple
- patients down the line. And who would ever know? The
ADA and AMA refuse to confront
- the issue - a criminally-negligent position to say the
- The numerous lawsuits already filed against doctors and
hospitals over the reuse
- of 'sterilized' surgical and medical instruments found
to have been used on CJD/Alzheimer's
- patients have already proven my point: that we are beyond
the age of sterilization as it applies
- to prion infection, transmission and death.
- Facts are facts: medical science must immediately abandon
the use of ALL reusable,
- invasive medical and dental instruments until and unless
a new, fool-proof method of
- guaranteed sterilization technology is developed. -
- Detection of Pathologic Prion Protein in the Olfactory
Epithelium in Sporadic Creutzfeldt-Jakob Disease
- Gianluigi Zanusso, M.D., Ph.D., Sergio Ferrari, M.D.,
Franco Cardone, Ph.D., Paolo Zampieri, M.D., Matteo Gelati, Ph.D., Michele
Fiorini, Ph.D., Alessia Farinazzo, Ph.D., Marina Gardiman, M.D., Tiziana
Cavallaro, M.D., Marina Bentivoglio, M.D., Pier Giorgio Righetti, Ph.D.,
Maurizio Pocchiari, M.D., Nicola Rizzuto, M.D., and Salvatore Monaco, M.D.
- Background Olfactory cortexes and the olfactory tracts
are involved in sporadic Creutzfeldt-Jakob disease. We examined peripheral
regions of the olfactory sensory pathway, including the olfactory mucosa,
to assess whether pathologic infectious prion protein (PrPSc) is deposited
in the epithelium lining the nasal cavity.
- Methods We studied nine patients with neuropathologically
confirmed sporadic Creutzfeldt-Jakob disease. We obtained the brain, the
cribriform plate with the attached olfactory mucosa, and the surrounding
respiratory epithelium at autopsy. Control samples of nasal mucosa were
obtained post mortem or at biopsy from age-matched control subjects and
from control patients with other neurodegenerative diseases. The olfactory
and respiratory mucosa and the intracranial olfactory system were analyzed
by light microscopy, immunohistochemistry, and Western blotting for pathological
changes and for deposition of PrPSc.
- Results In all nine patients with sporadic Creutzfeldt-Jakob
disease, PrPSc was found in the olfactory cilia and central olfactory pathway
but not in the respiratory mucosa. No PrPSc was detected in any of the
tissue samples from the 11 controls.
- Conclusions Our pathological and biochemical studies
show that PrPSc is deposited in the neuroepithelium of the olfactory mucosa
in patients with sporadic Creutzfeldt-Jakob disease, indicating that olfactory
biopsy may provide diagnostic information in living patients. The olfactory
pathway may represent a route of infection and a means of spreading prions.
- Source Information
- >From the Departments of Neurologic and Visual Sciences
(G.Z., S.F., M. Gelati, M.F., A.F., T.C., N.R., S.M.), Ear, Nose, and Throat
(P.Z.), Morphologic and Biomedical Sciences (M.B.), and Agricultural and
Industrial Biotechnologies (P.G.R.), Section of Clinical Neurology, University
of Verona, Verona; the Laboratory of Virology, Istituto Superiore di Sanità,
Rome (F.C., M.P.); and the Department of Pathology, University of Padua,
Padua (M. Gardiman) - all in Italy.
- Address reprint requests to Dr. Monaco at the Section
of Clinical Neurology, Department of Neurologic and Visual Sciences, Policlinico
G.B. Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy, or at email@example.com.
- The New England Journal of Medicine is owned, published,
and copyrighted © 2003
- Massachusetts Medical Society. All rights reserved.
- From Patricia Doyle, PhD
- Hello, Jeff - Maybe all of the programs we did happened
to get to the right people, ergo this Journal article. Someone might just
be listening to our shows. We talked about this probability a couple of
- I would also expect to hear confirmation from the elite
prionologist PhDs that transmission of CJD via dental instruments is a
reality. Also sexual transmission. Jeff, this is coming down the pike
and THEY cannot stop the news getting to the public. I guess some PhDs
decided that they cannot hide the news, so they want to be the first to
research the possibilities. Excellent. Now, maybe we can begin to do
something to stop the spread.
- As for saliva, we discussed it. Just look at the environment
with respect to CWD. Elk farms being held quarantined, etc.
- Thank you for sending the article. I will post it on
the message board.
- Patricia A. Doyle, PhD
- Please visit my "Emerging Diseases" message
- Zhan le Devlesa tai sastimasa
- Go with God and in Good Health